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MGST2

Description microsomal glutathione S-transferase 2
Image
GO Annotations Cellular Component
  • Nuclear Envelope
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Glutathione Transferase Activity
  • Leukotriene-C4 Synthase Activity
  • Glutathione Peroxidase Activity
  • Protein Binding
  • Enzyme Activator Activity
  • Oxidoreductase Activity
  • Transferase Activity
  • Lyase Activity
  • Identical Protein Binding
  • Glutathione Binding
Biological Process
  • Lipid Metabolic Process
  • Leukotriene Metabolic Process
  • Glutathione Biosynthetic Process
  • Leukotriene Biosynthetic Process
  • Response To Lipopolysaccharide
  • Carboxylic Acid Biosynthetic Process
  • Membrane Lipid Catabolic Process
  • Positive Regulation Of Inflammatory Response
  • Cellular Oxidant Detoxification
Pathways
  • Glutathione conjugation
  • Aflatoxin activation and detoxification
Drugs
  • Glutathione
Diseases
GWAS
  • Metabolite levels ( 23823483)
Interacting Genes 23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3
Entrez ID 4258
HPRD ID 03436
Ensembl ID ENSG00000085871
Uniprot IDs Q99735
PDB IDs 6SSR 6SSS 6SSU 6SSW
Enriched GO Terms of Interacting Partners?
  • SNAP Receptor Activity
  • Membrane
  • Membrane Fusion
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