MGST2

Gene Name		microsomal glutathione S-transferase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Enzyme Activator Activity
	Biological Process	Glutathione Biosynthetic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Oxidation-reduction Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Aflatoxin activation and detoxification Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: HDHD2
Entrez ID		4258
HPRD ID		03436
Ensembl ID		ENSG00000085871
Uniprot IDs		Q99735
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		2a ark axl believed biosynthesis cataract chaperones contributor defense downregulated glutathione groundwork hle hour hsp40 lens microarrays orp150 os peroxiredoxin perspective reductase respond return rnas subcategories thioredoxin trafficking transferase