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MGST2

Name microsomal glutathione S-transferase 2
Structure PDB 6SSR
Interactors 23 interactors: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3
GO Annotations Cellular Component
  • Nuclear Envelope
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Glutathione Transferase Activity
  • Leukotriene-C4 Synthase Activity
  • Glutathione Peroxidase Activity
  • Protein Binding
  • Enzyme Activator Activity
  • Oxidoreductase Activity
  • Transferase Activity
  • Lyase Activity
  • Identical Protein Binding
  • Glutathione Binding
Biological Process
  • Lipid Metabolic Process
  • Leukotriene Metabolic Process
  • Glutathione Biosynthetic Process
  • Leukotriene Biosynthetic Process
  • Response To Lipopolysaccharide
  • Carboxylic Acid Biosynthetic Process
  • Membrane Lipid Catabolic Process
  • Positive Regulation Of Inflammatory Response
  • Cellular Oxidant Detoxification
Pathways
  • Glutathione conjugation
  • Aflatoxin activation and detoxification
Drugs
  • Glutathione
GWAS
  • Metabolite levels ( 23823483 )
Entrez ID 4258
HPRD ID 03436
Ensembl ID ENSG00000085871
Uniprot IDs Q99735
PDB IDs 6SSR 6SSS 6SSU 6SSW
GO Terms Enriched among Interactors ?
  • SNAP Receptor Activity
  • Membrane
  • Membrane Fusion

© Madhavi K. Ganapathiraju 2012-2026