ZBTB42 and MKRN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB42	MKRN3
Description		zinc finger and BTB domain containing 42	makorin ring finger protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Ribonucleoprotein Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Organ Development	Protein Polyubiquitination Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Height ( 31562340) Menarche (age at onset) ( 25231870) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		49 interacting genes: AIRIM ANKS1A ASB6 ATG9A BLK CABP5 CATSPER1 CCDC102B CDR2L CIDEC CINP CLIC3 CRY2 FMR1 GEM GOLGA2 GUCD1 HSD3B7 HSF2BP KANK2 KCTD9 KRT40 MAGOHB MAPK1 MDFI MID2 MKRN3 MYLIP NCK2 NDOR1 NOC4L OAZ3 OSGIN1 OSTF1 OTX1 PIN1 PLA2G6 POLR1C RAD51D SNX18 SPG21 TRAPPC2L TRIM68 TTC23 UBASH3A USHBP1 ZBTB16 ZBTB7B ZNF330	181 interacting genes: ACOT11 ADAMTSL4 ADRA2C ANKRD11 ANTKMT APEX2 AQP1 ARID5A ARMC5 ATOSB AVPI1 BATF2 BCL2L11 BEX2 BLZF1 BPIFA1 C21orf58 CCDC120 CCDC185 CCDC187 CCDC33 CDCA4 CEP70 CERCAM CIMAP1B CRACR2A CYSRT1 DDIT4L ECM1 ECSIT EFEMP1 ENKD1 ERCC1 FAM110A FAM124B FARS2 GADD45GIP1 GATA1 GEM GOLGA6A GRAP2 HCK HGS HOXA1 HOXD12 HSF2BP HSF4 IGF1 IKZF3 INO80B KANK2 KIF1A KIFC3 KLF1 KLHL38 KRT34 KRT75 KRT86 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LAGE3 LASP1 LRSAM1 MAGED1 MBD3 MCCD1 MDM2 MDM4 MEOX1 MEOX2 MGAT5B MIF4GD MNAT1 MORN3 MRPL38 MRPS6 MYOZ2 NABP1 NDE1 NDUFB7 NKAPD1 NME4 ODAD4 PABPC4 PEX10 PEX5 PKN1 POLR1C POMC PRKAA2 PRPF31 PRR22 PRR35 PSMA1 PSMB1 PTH1R PTK6 RASD1 RBM41 RBPMS RBPMS2 RIBC1 RNF10 RNF166 RNF32 RNF7 RSPH1 RSPO4 RTP5 SCNM1 SF1 SFN SLPI SMARCD1 SMYD3 SNRPC SORBS3 SPATA8 SPMIP5 STH STMN3 STN1 SYNGAP1 TADA2A TASOR2 TCEA2 TCHP TCL1B TENT5B TFAP2A TFIP11 TLE5 TPRX1 TRAF2 TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TSGA10IP TSPAN4 TTC23 TXNDC11 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W UQCC2 USHBP1 VPS9D1 WDR25 WWOX YPEL3 ZBTB42 ZFC3H1 ZFP57 ZIM2 ZNF34 ZNF414 ZNF587 ZNF688 ZNF835
Entrez ID		100128927	7681
HPRD ID		19441	04836
Ensembl ID		ENSG00000179627	ENSG00000179455
Uniprot IDs		B2RXF5	Q13064
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Binding Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein K63-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Modification-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Protein K48-linked Ubiquitination Regulation Of Nucleobase-containing Compound Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription UBC13-MMS2 Complex Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Activity Nucleus Protein Modification Process Ubiquitin Conjugating Enzyme Complex Intermediate Filament Macromolecule Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Protein Polyubiquitination Transferase Activity Positive Regulation Of Protein K63-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Gene Expression Zinc Ion Binding Error-free Postreplication DNA Repair Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Regulation Of Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity Regulation Of Protein K63-linked Ubiquitination Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Proteasomal Protein Catabolic Process TORC1 Signaling NEDD8 Ligase Activity ISG15 Transferase Activity
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