ZBTB42 and SNX18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB42	SNX18
Description		zinc finger and BTB domain containing 42	sorting nexin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Endosome Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Phosphatidylinositol Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Organ Development	Mitotic Cell Cycle Mitotic Cytokinesis Endocytosis Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity Cell Division Plasma Membrane Tubulation Positive Regulation Of Autophagosome Assembly
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		49 interacting genes: AIRIM ANKS1A ASB6 ATG9A BLK CABP5 CATSPER1 CCDC102B CDR2L CIDEC CINP CLIC3 CRY2 FMR1 GEM GOLGA2 GUCD1 HSD3B7 HSF2BP KANK2 KCTD9 KRT40 MAGOHB MAPK1 MDFI MID2 MKRN3 MYLIP NCK2 NDOR1 NOC4L OAZ3 OSGIN1 OSTF1 OTX1 PIN1 PLA2G6 POLR1C RAD51D SNX18 SPG21 TRAPPC2L TRIM68 TTC23 UBASH3A USHBP1 ZBTB16 ZBTB7B ZNF330	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		100128927	112574
HPRD ID		19441	15407
Ensembl ID		ENSG00000179627	ENSG00000178996
Uniprot IDs		B2RXF5	Q96RF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Regulation Of Pro-B Cell Differentiation Regulation Of Lymphoid Progenitor Cell Differentiation Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding SH3 Domain Binding Regulation Of T Cell Differentiation In Thymus B Cell Homeostasis Macroautophagy Regulation Of Hematopoietic Progenitor Cell Differentiation
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