UBE2U and CADPS2

Data Source:
BioGRID (two hybrid)

		UBE2U	CADPS2
Description		ubiquitin conjugating enzyme E2 U	calcium dependent secretion activator 2
Image			No pdb structure
GO Annotations	Cellular Component	HULC Complex	Nucleoplasm Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Lipid Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Severe bacterial meningitis ( 31092817)	Adult body size ( 32376654) Attention deficit hyperactivity disorder ( 32279069 30478444) Brain structure ( 20171287) General risk tolerance (MTAG) ( 30643258) Menarche (age at onset) ( 25231870) Number of sexual partners ( 30643258) Serum sulfate level ( 27412988) Smoking status (ever vs never smokers) ( 30643258) Waist circumference ( 28552196)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	15 interacting genes: BDNF DMD DRD2 MEGF10 SRPK2 TSPOAP1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U UBE2W
Entrez ID		148581	93664
HPRD ID		14599	12996
Ensembl ID		ENSG00000177414	ENSG00000081803
Uniprot IDs		A0A140VJY9 Q5VVX9	B7ZM57 Q86UW7 X5DNG0
PDB IDs		1YRV
Enriched GO Terms of Interacting Partners?
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