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UBE2U and KAT6A
Data Source:
BioGRID
(two hybrid)
UBE2U
KAT6A
Description
ubiquitin conjugating enzyme E2 U
lysine acetyltransferase 6A
Image
GO Annotations
Cellular Component
HULC Complex
Nucleosome
Nucleus
Nucleoplasm
Nucleolus
Cytosol
PML Body
Nuclear Speck
MOZ/MORF Histone Acetyltransferase Complex
Molecular Function
Protein Binding
ATP Binding
Ubiquitin Conjugating Enzyme Activity
DNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
Acetyltransferase Activity
Histone Binding
Biological Process
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
DNA Packaging
Nucleosome Assembly
Protein Acetylation
Histone Acetylation
Myeloid Cell Differentiation
Histone H3 Acetylation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Senescence
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
HATs acetylate histones
Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS
Severe bacterial meningitis (
31092817
)
Sleep duration (
30531941
)
Interacting Genes
68 interacting genes:
ANAPC11
BARD1
BFAR
CADPS2
CBL
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
UBA1
VPS11
VPS41
ZSWIM2
19 interacting genes:
AKT1
ATN1
ATXN1
CREBBP
H3-4
H3-5
H3C1
H3C14
H4-16
H4C1
H4C9
HEMGN
MAFK
PML
RERE
RUNX1
SPI1
TP53
UBE2U
Entrez ID
148581
7994
HPRD ID
14599
03244
Ensembl ID
ENSG00000177414
ENSG00000083168
Uniprot IDs
A0A140VJY9
Q5VVX9
A5PKX7
A5PLL3
Q92794
PDB IDs
1YRV
1M36
2LN0
2OZU
2RC4
3V43
4LJN
4LK9
4LKA
4LLB
5B75
5B76
5B77
5B78
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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