CYB5A and CYB5R3

Number of citations of the paper that reports this interaction (PubMedID 221468)
6

Data Source:
HPRD (in vitro)

		CYB5A	CYB5R3
Description		cytochrome b5 type A	cytochrome b5 reductase 3
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GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen
	Molecular Function	Cytochrome-c Oxidase Activity Enzyme Binding Heme Binding Metal Ion Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding
	Biological Process	L-ascorbic Acid Metabolic Process Electron Transport Chain Response To Cadmium Ion Proton Transmembrane Transport	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process
Pathways		Vitamin C (ascorbate) metabolism	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		Dimethyl Propionate Ester Heme	NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia	Methemoglobinemia
GWAS		Blood protein levels ( 30072576)	Initial pursuit acceleration ( 29064472)
Interacting Genes		14 interacting genes: CYB5R3 CYCS CYP17A1 CYP1A1 CYP1A2 CYP2A6 CYP2D6 CYP2E1 CYP2W1 CYP3A4 CYP4A11 POR SCD UGT1A4	11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3
Entrez ID		1528	1727
HPRD ID		08941	08942
Ensembl ID		ENSG00000166347	ENSG00000100243
Uniprot IDs		A0A384ME44 P00167	P00387
PDB IDs		2I96	1M91 1UMK
Enriched GO Terms of Interacting Partners?
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