CYB5R3 and XPNPEP3

		CYB5R3	XPNPEP3
Description		cytochrome b5 reductase 3	X-prolyl aminopeptidase 3
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen	Cytoplasm Mitochondrion
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding	Aminopeptidase Activity Protein Binding Manganese Ion Binding Protein Homodimerization Activity Metalloaminopeptidase Activity
	Biological Process	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process	Glomerular Filtration Proteolysis Protein Processing
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia	Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Initial pursuit acceleration ( 29064472)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) C-reactive protein levels ( 30388399) Experiencing mood swings ( 29500382) Schizophrenia ( 28991256)
Interacting Genes		11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3	1 interacting genes: CYB5R3
Entrez ID		1727	63929
HPRD ID		08942	10052
Ensembl ID		ENSG00000100243	ENSG00000196236
Uniprot IDs		P00387	A0A087X0Z2 Q9NQH7
PDB IDs		1M91 1UMK	5X49
Enriched GO Terms of Interacting Partners?
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