CYB5A and CYP4A11

Number of citations of the paper that reports this interaction (PubMedID 10660572)
57

Data Source:
BioGRID (enzymatic study)

		CYB5A	CYP4A11
Description		cytochrome b5 type A	cytochrome P450 family 4 subfamily A member 11
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Endoplasmic Reticulum Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Cytochrome-c Oxidase Activity Enzyme Binding Heme Binding Metal Ion Binding	Iron Ion Binding Arachidonic Acid Epoxygenase Activity Alkane 1-monooxygenase Activity Heme Binding Leukotriene-B4 20-monooxygenase Activity Aromatase Activity
	Biological Process	L-ascorbic Acid Metabolic Process Electron Transport Chain Response To Cadmium Ion Proton Transmembrane Transport	Long-chain Fatty Acid Metabolic Process Renal Water Homeostasis Pressure Natriuresis Fatty Acid Metabolic Process Leukotriene Metabolic Process Regulation Of Lipid Metabolic Process Arachidonic Acid Metabolic Process Epoxygenase P450 Pathway Oxylipin Biosynthetic Process Positive Regulation Of Icosanoid Secretion Leukotriene B4 Catabolic Process Sodium Ion Homeostasis Oxidation-reduction Process Omega-hydroxylase P450 Pathway
Pathways		Vitamin C (ascorbate) metabolism	PPARA activates gene expression Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Drugs		Dimethyl Propionate Ester Heme	NADH
Diseases		Methemoglobinemia
GWAS		Blood protein levels ( 30072576)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		14 interacting genes: CYB5R3 CYCS CYP17A1 CYP1A1 CYP1A2 CYP2A6 CYP2D6 CYP2E1 CYP2W1 CYP3A4 CYP4A11 POR SCD UGT1A4	2 interacting genes: CYB5A PIK3R1
Entrez ID		1528	1579
HPRD ID		08941	03201
Ensembl ID		ENSG00000166347	ENSG00000187048
Uniprot IDs		A0A384ME44 P00167	Q02928
PDB IDs		2I96
Enriched GO Terms of Interacting Partners?
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