CYB5R3 and L3MBTL2

		CYB5R3	L3MBTL2
Description		cytochrome b5 reductase 3	L3MBTL histone methyl-lysine binding protein 2
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen	Nucleus Nucleoplasm
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation	SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia
GWAS		Initial pursuit acceleration ( 29064472)	Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		1727	83746
HPRD ID		08942	13954
Ensembl ID		ENSG00000100243	ENSG00000100395
Uniprot IDs		P00387	A0A0S2Z5X6 Q969R5
PDB IDs		1M91 1UMK	2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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