NMB - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	CCNO	cyclin O
Novel	CORO2B	coronin 2B
Novel	FBXL22	F-box and leucine rich repeat protein 22	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Novel	GLCE	glucuronic acid epimerase	HS-GAG biosynthesis
Novel	KIF23	kinesin family member 23	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Novel	MAP2K5	mitogen-activated protein kinase kinase 5	Signalling to ERK5	Fostamatinib Pimasertib
Novel	MRPS5	mitochondrial ribosomal protein S5	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Novel	PTPRZ1	protein tyrosine phosphatase receptor type Z1	Other interleukin signaling MDK and PTN in ALK signaling
	BIRC2	baculoviral IAP repeat containing 2	Apoptotic cleavage of cellular proteins NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment RIPK1-mediated regulated necrosis TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway TNFR2 non-canonical NF-kB pathway Regulation of necroptotic cell death TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Ub-specific processing proteases IKK complex recruitment mediated by RIP1
	GADD45G	growth arrest and DNA damage inducible gamma
	NMBR	neuromedin B receptor	Peptide ligand-binding receptors G alpha (q) signalling events
	TPP1	tripeptidyl peptidase 1	XBP1(S) activates chaperone genes		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD) Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)

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