NMB and CCNO

		NMB	CCNO
Description		neuromedin B	cyclin O
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Neuron Projection	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Centriolar Satellite
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Immune System Process Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interferon-alpha Production Innate Immune Response Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonate Secretion Positive Regulation Of Osteoclast Proliferation Antiviral Innate Immune Response Sneeze Reflex Leydig Cell Proliferation Sensory Perception Of Itch Positive Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Testosterone Secretion	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Spermatogenesis Single Fertilization Cell Projection Organization Cell Division Cilium Assembly Seminiferous Tubule Development Multi-ciliated Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Cocaine dependence ( 31212010)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	5 interacting genes: HSPB1 ITSN1 PCNA RPA2 VAV2
Entrez ID		4828	10309
HPRD ID		01210	06375
Ensembl ID		ENSG00000197696	ENSG00000152669
Uniprot IDs		P08949	P22674
PDB IDs		1C98 1C9A 8H0P
Enriched GO Terms of Interacting Partners?			Vascular Endothelial Growth Factor Receptor Signaling Pathway Mismatch Repair Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Sensory Perception Of Itch Sneeze Reflex Positive Regulation Of Testosterone Secretion Neuromedin B Receptor Binding Positive Regulation Of Osteoclast Proliferation Leydig Cell Proliferation Positive Regulation Of Hormone Secretion PCNA Complex Damaged DNA Binding PCNA-p21 Complex Replisome Telomere Maintenance DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Cellular Response To Xenobiotic Stimulus Dinucleotide Insertion Or Deletion Binding DNA Replication Telomere Organization Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Deoxyribonuclease Activity Leading Strand Elongation Positive Regulation Of Caveolin-mediated Endocytosis Intracellular Signal Transduction Chromosome, Telomeric Region Regulation Of Cell Communication Regulation Of Signaling Regulation Of Protein Kinase C Signaling Regulation Of Intracellular Signal Transduction MutLalpha Complex Binding Telomere Maintenance Via Semi-conservative Replication Guanyl-nucleotide Exchange Factor Activity Regulation Of Caveolin-mediated Endocytosis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Regulation Of DNA Repair Anterograde Axonal Protein Transport Positive Regulation Of DNA-directed DNA Polymerase Activity Postsynaptic Endocytic Zone Positive Regulation Of Growth Hormone Secretion Regulation Of Hormone Secretion G-rich Strand Telomeric DNA Binding Postsynaptic Actin Cytoskeleton Signal Transduction Protein Transport Along Microtubule Contractile Muscle Fiber
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