NMB and CORO2B

		NMB	CORO2B
Description		neuromedin B	coronin 2B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Neuron Projection	Cytoplasm Cytoskeleton Focal Adhesion Actin Cytoskeleton Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Actin Binding Protein Binding Vinculin Binding Actin Filament Binding Talin Binding
	Biological Process	Immune System Process Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interferon-alpha Production Innate Immune Response Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonate Secretion Positive Regulation Of Osteoclast Proliferation Antiviral Innate Immune Response Sneeze Reflex Leydig Cell Proliferation Sensory Perception Of Itch Positive Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Testosterone Secretion	Regulation Of Glomerular Filtration Negative Regulation Of Cell-substrate Adhesion Actin Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Focal Adhesion Assembly Negative Regulation Of Stress Fiber Assembly Regulation Of Cellular Response To Stress Negative Regulation Of Establishment Of Protein Localization Positive Regulation Of Establishment Of Protein Localization
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Cognitive performance ( 19734545) PR interval ( 32439900) Systolic blood pressure ( 26969751)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	5 interacting genes: ACTA1 APPBP2 RSPH1 TSC22D1 VCL
Entrez ID		4828	10391
HPRD ID		01210	05416
Ensembl ID		ENSG00000197696	ENSG00000103647
Uniprot IDs		P08949	Q9UQ03
PDB IDs		1C98 1C9A 8H0P
Enriched GO Terms of Interacting Partners?			Sensory Perception Of Itch Sneeze Reflex Positive Regulation Of Testosterone Secretion Neuromedin B Receptor Binding Positive Regulation Of Osteoclast Proliferation Leydig Cell Proliferation Regulation Of Protein Localization To Adherens Junction Inner Dense Plaque Of Desmosome Podosome Ring Terminal Web Outer Dense Plaque Of Desmosome Radial Spoke Head 1 Radial Spoke Head 3 Cytoskeleton Positive Regulation Of Respiratory Gaseous Exchange Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Regulation Of Protein Localization To Cell-cell Junction Molecular Adaptor Activity Negative Regulation Of Hematopoietic Stem Cell Proliferation Radial Spoke Head Cell-substrate Junction Outer Dense Fiber Apical Junction Assembly Zonula Adherens Fascia Adherens
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