NMB and GLCE

		NMB	GLCE
Description		neuromedin B	glucuronic acid epimerase
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Neuron Projection	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Calcium Ion Binding Isomerase Activity Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Metal Ion Binding Heparosan-N-sulfate-glucuronate 5-epimerase Activity
	Biological Process	Immune System Process Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interferon-alpha Production Innate Immune Response Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonate Secretion Positive Regulation Of Osteoclast Proliferation Antiviral Innate Immune Response Sneeze Reflex Leydig Cell Proliferation Sensory Perception Of Itch Positive Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Testosterone Secretion	Positive Regulation Of Cell Population Proliferation Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Proteoglycan Biosynthetic Process Negative Regulation Of Cell Projection Organization Positive Regulation Of SMAD Protein Signal Transduction
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	HS-GAG biosynthesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1
Entrez ID		4828	26035
HPRD ID		01210	07020
Ensembl ID		ENSG00000197696	ENSG00000138604
Uniprot IDs		P08949	O94923
PDB IDs		1C98 1C9A 8H0P	6HZZ 6I01 6I02
Enriched GO Terms of Interacting Partners?			Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Population Proliferation Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Prostate Epithelial Cord Elongation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Fibroblast Growth Factor Receptor Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAPK Cascade Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Prostate Gland Growth Regulation Of Catalytic Activity Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Signal Transduction Branch Elongation Of An Epithelium Regulation Of MAPK Cascade Stem Cell Differentiation Positive Regulation Of Metabolic Process Axis Elongation Regulation Of Metabolic Process Protein Tyrosine Kinase Activity Fibroblast Growth Factor Binding Prostate Gland Epithelium Morphogenesis Response To Lipid Morphogenesis Of A Branching Epithelium Morphogenesis Of Embryonic Epithelium Morphogenesis Of A Branching Structure Animal Organ Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epithelial Tube Formation Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Signal Transduction Cellular Response To Epidermal Growth Factor Stimulus Organ Growth Positive Regulation Of Macromolecule Biosynthetic Process Response To Epidermal Growth Factor Regulation Of Morphogenesis Of A Branching Structure Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow
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