Search Results for: NGEF

20 interactions involving NGEF - neuronal guanine nucleotide exchange factor found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel SEPTIN2 septin 2
  • Anchoring of the basal body to the plasma membrane
Novel TTK TTK protein kinase
  • Pyrazolanthrone
  • Fostamatinib
  • BOS172722
Novel USP25 ubiquitin specific peptidase 25
  • Ub-specific processing proteases
Novel YIPF3 Yip1 domain family member 3
ATP5F1C ATP synthase F1 subunit gamma
  • Formation of ATP by chemiosmotic coupling
  • Cristae formation
  • Mitochondrial protein degradation
  • Quercetin
  • 1-ACETYL-2-CARBOXYPIPERIDINE
  • AUROVERTIN B
  • Piceatannol
  • N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
C7orf25 chromosome 7 open reading frame 25
C8orf33 chromosome 8 open reading frame 33
EPHA4 EPH receptor A4
  • EPH-Ephrin signaling
  • EPH-Ephrin signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • EPH-ephrin mediated repulsion of cells
  • EPH-ephrin mediated repulsion of cells
  • Somitogenesis
  • Fostamatinib
FAM118B family with sequence similarity 118 member B
HCK HCK proto-oncogene, Src family tyrosine kinase
  • Nef and signal transduction
  • FCGR activation
  • Regulation of signaling by CBL
  • Regulation of signaling by CBL
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated phagocytosis
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF1 (M-CSF) in myeloid cells
  • Inactivation of CSF3 (G-CSF) signaling
  • Inactivation of CSF3 (G-CSF) signaling
  • FLT3 signaling through SRC family kinases
  • 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
  • Phosphonotyrosine
  • Quercetin
  • Bosutinib
  • Fostamatinib
LCOR ligand dependent nuclear receptor corepressor
MRPL44 mitochondrial ribosomal protein L44
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
  • Mitochondrial ribosome-associated quality control
NUDT21 nudix hydrolase 21
  • mRNA 3'-end processing
  • Processing of Capped Intron-Containing Pre-mRNA
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
RHOA ras homolog family member A
  • GPVI-mediated activation cascade
  • Axonal growth inhibition (RHOA activation)
  • PI3K/AKT activation
  • Axonal growth stimulation
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • G beta:gamma signalling through PI3Kgamma
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • PCP/CE pathway
  • G alpha (12/13) signalling events
  • Sema4D mediated inhibition of cell attachment and migration
  • Sema4D induced cell migration and growth-cone collapse
  • Sema4D induced cell migration and growth-cone collapse
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases activate CIT
  • RHO GTPases activate KTN1
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • Ovarian tumor domain proteases
  • ERBB2 Regulates Cell Motility
  • Neutrophil degranulation
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • RHOA GTPase cycle
  • SLIT2:ROBO1 increases RHOA activity
  • RHOC GTPase cycle
  • Guanosine-5'-Diphosphate
SH2D1A SH2 domain containing 1A
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
SMO smoothened, frizzled class receptor
  • Class B/2 (Secretin family receptors)
  • Hedgehog 'off' state
  • BBSome-mediated cargo-targeting to cilium
  • Hedgehog 'on' state
  • Activation of SMO
  • Activation of SMO
  • Fluocinonide
  • Halcinonide
  • Vismodegib
  • Sonidegib
  • Glasdegib
  • Basal cell carcinoma
TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D
  • SIRT1 negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Promoter Escape
  • RNA Polymerase I Transcription Termination
TRIM55 tripartite motif containing 55
TRIM63 tripartite motif containing 63
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Antigen processing: Ubiquitination & Proteasome degradation
USP7 ubiquitin specific peptidase 7
  • Ub-specific processing proteases
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Regulation of TP53 Degradation
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • Regulation of PTEN localization

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