NGEF and MRPL44

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NGEF	MRPL44
Gene Name		neuronal guanine nucleotide exchange factor	mitochondrial ribosomal protein L44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Growth Cone	Cellular_component Mitochondrial Inner Membrane Ribosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity	Ribonuclease III Activity Poly(A) RNA Binding
	Biological Process	Small GTPase Mediated Signal Transduction Axon Guidance Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Neurotrophin TRK Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis Apoptotic Signaling Pathway	RNA Processing Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Signaling by GPCR Signalling by NGF Axon guidance Cell death signalling via NRAGE, NRIF and NADE p75 NTR receptor-mediated signalling Rho GTPase cycle EPHA-mediated growth cone collapse GPCR downstream signaling NRAGE signals death through JNK Signaling by Rho GTPases EPH-Ephrin signaling G alpha (12/13) signalling events	Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATP5C1 C7orf25 C8orf33 EPHA4 FAM118B MRPL44 NUDT21 TAF1D	15 interactors: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PPAP2C PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235
Entrez ID		25791	65080
HPRD ID		10442	14763
Ensembl ID		ENSG00000066248	ENSG00000135900
Uniprot IDs		B4DDI2 Q8N5V2	Q9H9J2
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription, Termination Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon Negative Regulation Of Axon Regeneration
Tagcloud ?		1h aangef amide asn asp asparaginyl aspartyl backbone capillary carry ce deposited deposits deprotonation inventory isoasp isoaspartate isomerization isopeptide isotope kd2o kh2o limiting notion peptides proton succinimide validate velocity
Tagcloud (Difference) ?		1h aangef amide asn asp asparaginyl aspartyl backbone capillary carry ce deposited deposits deprotonation inventory isoasp isoaspartate isomerization isopeptide isotope kd2o kh2o limiting notion peptides proton succinimide validate velocity
Tagcloud (Intersection) ?