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PPP4R1 and PPP4C
Number of citations of the paper that reports this interaction (PMID
18715871
)
21
Data Source:
HPRD
(in vitro, in vivo)
PPP4R1
PPP4C
Gene Name
protein phosphatase 4, regulatory subunit 1
protein phosphatase 4, catalytic subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Protein Phosphatase 4 Complex
Nucleus
Nucleoplasm
Cytoplasm
Microtubule Organizing Center
Plasma Membrane
Protein Phosphatase 4 Complex
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Binding
Protein Phosphatase Type 4 Regulator Activity
NF-kappaB-inducing Kinase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Metal Ion Binding
Biological Process
Protein Phosphorylation
Signal Transduction
Dephosphorylation
Regulation Of Catalytic Activity
Regulation Of Double-strand Break Repair Via Homologous Recombination
Dephosphorylation
NIK/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
CEP63
DISC1
HDAC3
PPP4C
20 interactors:
CCDC6
DHX38
HDAC3
IGBP1
JUN
NFKB1
PPP2R1A
PPP2R5D
PPP4R1
PPP4R2
PPP4R4
REL
RELA
SMEK2
TIPRL
TK1
TMSB4X
TP53
TRAF6
TRIM28
Entrez ID
9989
5531
HPRD ID
05366
03615
Ensembl ID
ENSG00000154845
ENSG00000149923
Uniprot IDs
Q8TF05
P60510
PDB IDs
Enriched GO Terms of Interacting Partners
?
Microtubule Cytoskeleton Organization
Spindle Assembly
Microtubule-based Process
Spindle Organization
Cytoskeleton Organization
Intracellular Signal Transduction
Centriole Replication
Regulation Of Double-strand Break Repair Via Homologous Recombination
Organelle Assembly
Signal Transduction
Cellular Response To Fluid Shear Stress
Mitochondrial Calcium Ion Homeostasis
Signaling
Regulation Of Synapse Maturation
Centriole Assembly
Cell Communication
Positive Regulation Of TOR Signaling
TOR Signaling
Regulation Of Interleukin-12 Biosynthetic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Toll-like Receptor 4 Signaling Pathway
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cellular Metabolic Process
Response To Growth Factor
Toll-like Receptor Signaling Pathway
Positive Regulation Of Interleukin-12 Biosynthetic Process
NIK/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Activation Of Innate Immune Response
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Interleukin-12 Production
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Innate Immune Response
Membrane Protein Intracellular Domain Proteolysis
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cell Death
Regulation Of Catalytic Activity
Response To Interleukin-1
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin Signaling Pathway
Response To Organic Substance
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Innate Immune Response
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Regulation Of Cytokine Biosynthetic Process
Innate Immune Response
Immune System Process
Membrane Protein Proteolysis
Transcription From RNA Polymerase II Promoter
Immune Response
Tagcloud
?
6j
acpp
canonical
carcinogenic
cdk5
delineate
e2f6
elf1
glands
gprc5a
hindered
ingenuity
ionizing
ipa
map2
mapk12
mapped
microarray
nab2
persistently
perturbed
plcg1
radiation
runx1
scarcity
sema4d
stathmin1
surgically
undertook
Tagcloud (Difference)
?
6j
acpp
canonical
carcinogenic
cdk5
delineate
e2f6
elf1
glands
gprc5a
hindered
ingenuity
ionizing
ipa
map2
mapk12
mapped
microarray
nab2
persistently
perturbed
plcg1
radiation
runx1
scarcity
sema4d
stathmin1
surgically
undertook
Tagcloud (Intersection)
?