MED12 and CDK8

  • Number of citations of the paper that reports this interaction (PMID 20720539)
  • 313
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo)

MED12

CDK8

Gene Name mediator complex subunit 12 cyclin-dependent kinase 8
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 17 interactors: CDK8 ESR1 ESR2 GLI3 LYST MED1 MED13 MED26 MED29 MED8 MED9 MYC NANOG PPARGC1A SOX9 SREBF1 VDR 29 interactors: BCL6 CCNC CCNH CDKN2B CTD CTDP1 ERCC3 ESR1 ESR2 HIST2H3C MAML1 MBP MED12 MED21 MED25 MED26 MED8 MED9 MYC NRIP1 POLR2A SGCG SMAD2 SMAD3 SMARCA4 SREBF1 SUZ12 TOP1 TP53
Entrez ID 9968 1024
HPRD ID 02176 04422
Ensembl ID ENSG00000184634 ENSG00000132964
Uniprot IDs Q93074 P49336
PDB IDs 3RGF 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accounting  actionable  amplifications  borderline  cnas  confined  defines  deleterious  drive  druggable  exclusively  expands  ffpe  fibroepithelial  formalin  g44  grades  hotspot  identifies  landscape  mutational  neurofibromin  nf1  ngs  phyllodes  rb1  retinoblastoma  spanning  suppressors 
absent  acetyltransferase  acetyltransferases  cbp  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  interacts  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi  yeast 
Tagcloud (Difference) ?
accounting  actionable  amplifications  borderline  cnas  confined  defines  deleterious  drive  druggable  exclusively  expands  ffpe  fibroepithelial  formalin  g44  grades  hotspot  identifies  landscape  mutational  neurofibromin  nf1  ngs  phyllodes  rb1  retinoblastoma  spanning  suppressors 
absent  acetyltransferase  acetyltransferases  cbp  chromatography  competent  complex  contains  conventional  directed  elongation  form  histone  homolog  ii  importantly  interacts  nonphosphorylated  notably  pcaf  polymerase  purified  remodeling  rna  snf  srb  srb10  swi  yeast 
Tagcloud (Intersection) ?