MSL1 and RNF40

Number of citations of the paper that reports this interaction (PubMedID 24837678)
66

Data Source:
BioGRID (pull down)

		MSL1	RNF40
Description		MSL complex subunit 1	ring finger protein 40
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck MSL Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane HULC Complex
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Positive Regulation Of DNA-templated Transcription	Chromatin Organization Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Asthma ( 31619474)	Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	27 interacting genes: AMOTL2 ATM CCDC146 CDC73 DUSP29 EEF1D H2AC4 H2BC3 ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL PKNOX1 RB1 RPA1 RPA2 TRIM51 UBE2A UBE2B UBE2D2 UBE2I UBE2L6 ZCCHC12 ZNF451
Entrez ID		339287	9810
HPRD ID		19425	07411
Ensembl ID		ENSG00000188895	ENSG00000103549
Uniprot IDs		B3KWR7 J3KSZ8 J3QQY0 Q68DK7	A8K6K1 O75150
PDB IDs		4B7Y 4B86 4DNC	8GUI 8GUJ 8IEJ
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of Cell Cycle Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Import Into Nucleus Chromatin Binding HULC Complex Positive Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Importin-alpha Family Protein Binding Positive Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Double-strand Break Repair Transcription Coactivator Activity Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process NuA4 Histone Acetyltransferase Complex Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Metabolic Process Protein Localization To Nucleus Fibroblast Proliferation Reproductive Structure Development Negative Regulation Of Protein Kinase C Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Stereocilium Shaft Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Regulation Of Macromolecule Metabolic Process Male Germ Cell Nucleus Developmental Process Involved In Reproduction Regulation Of DNA Repair Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Response To Stress Helper T Cell Diapedesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Ubiquitin-protein Transferase Activity Regulation Of Primary Metabolic Process	Ubiquitin Conjugating Enzyme Activity Protein Localization To Chromosome PML Body Ubiquitin-like Protein Transferase Activity Chromosome, Telomeric Region Positive Regulation Of MRNA 3'-end Processing HULC Complex Chromatin Organization Nucleus Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Protein Modification By Small Protein Conjugation Protein Polyubiquitination Telomere Localization Regulation Of MRNA 3'-end Processing G-rich Strand Telomeric DNA Binding Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Macromolecule Catabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition DNA Replication Factor A Complex Chromosome Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Post-translational Protein Modification Macromolecule Metabolic Process Negative Regulation Of Mitotic Cell Cycle Nucleoplasm Negative Regulation Of Cell Cycle Phase Transition Site Of Double-strand Break Chromatin Remodeling Telomere Maintenance Proteolysis Involved In Protein Catabolic Process Histone MRNA Metabolic Process Response To Radiation Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Localization To Site Of Double-strand Break Sperm Axoneme Assembly Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Process Mismatch Repair Telomere Organization DNA Repair MRNA 3'-end Processing Double-strand Break Repair Via Homologous Recombination Ubiquitin Protein Ligase Binding Recombinational Repair Regulation Of DNA Recombination Positive Regulation Of RNA Binding
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