MSL1 and RNF40

Number of citations of the paper that reports this interaction (PMID 24837678)
0

Data Source:
BioGRID (pull down)

		MSL1	RNF40
Gene Name		male-specific lethal 1 homolog (Drosophila)	ring finger protein 40, E3 ubiquitin protein ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm MSL Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane HULC Complex Neuron Projection
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Syntaxin-1 Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Chromatin Organization Histone H4-K16 Acetylation	Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Histone H2B Ubiquitination
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: CRKL FCHSD2 HIST2H2BE HORMAD1 KAT8 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	18 interactors: AMOTL2 ATM CCDC146 CDC73 HIST2H2BE ITSN1 MSL1 NCBP1 RB1 SFR1 TRIM51 UBE2A UBE2B UBE2E1 UBE2I UBE2L6 WAC ZNF451
Entrez ID		339287	9810
HPRD ID		19425	07411
Ensembl ID		ENSG00000188895	ENSG00000103549
Uniprot IDs		B3KWR7 J3KSZ8 Q68DK7	A8K6K1 F8W8Z4 O75150
PDB IDs		4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Protein Monoubiquitination Histone H2B Ubiquitination Chromatin Modification Histone Monoubiquitination Histone Ubiquitination Histone Modification Organelle Organization Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Acetylation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Import Intracellular Transport Of Virus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Histone Methylation Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein Ubiquitination RNA Metabolic Process Cellular Protein Modification Process Regulation Of Histone Methylation Histone H4 Acetylation Protein Modification By Small Protein Conjugation Regulation Of Homologous Chromosome Segregation Positive Regulation Of Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Histone Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Meiotic Recombination Checkpoint Positive Regulation Of Vitamin D Receptor Signaling Pathway	Histone Ubiquitination Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Protein Monoubiquitination Histone H2B Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone Monoubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition ISG15-protein Conjugation Organelle Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Proteasomal Protein Catabolic Process Regulation Of Chromosome Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Chromosome Organization Cell Cycle Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone H2A Ubiquitination Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Negative Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Mitotic Nuclear Division Catabolic Process Histone MRNA Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Postreplication Repair
Tagcloud ?		alters aspect comprise correlating cryptic exonic h2b h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing talk transcribed trimethylation u2	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Difference) ?		alters aspect comprise correlating cryptic exonic h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing transcribed trimethylation u2	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands traditionally usp22 usp44 usp7 viewed
Tagcloud (Intersection) ?		h2b talk