MSL1 and SNW1

Number of citations of the paper that reports this interaction (PMID 19650074)
6

Data Source:
BioGRID (two hybrid)

		MSL1	SNW1
Gene Name		male-specific lethal 1 homolog (Drosophila)	SNW domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm MSL Complex	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Positive Transcription Elongation Factor Complex B Nuclear Matrix Catalytic Step 2 Spliceosome SMAD3-SMAD4 Protein Complex
	Molecular Function		Transcription Coactivator Activity Transcription Corepressor Activity Notch Binding Protein Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Chromatin Organization Histone H4-K16 Acetylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Gene Expression Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Protein-Protein Interactions		17 interactors: CRKL FCHSD2 HIST2H2BE HORMAD1 KAT8 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	58 interactors: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOR1 NCOR2 NHP2L1 NOTCH1 NOTCH3 NR0B1 NR0B2 PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SRC TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR ZSCAN1
Entrez ID		339287	22938
HPRD ID		19425	04340
Ensembl ID		ENSG00000188895	ENSG00000100603
Uniprot IDs		B3KWR7 J3KSZ8 Q68DK7	G3V3A4 Q13573
PDB IDs		4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Protein Monoubiquitination Histone H2B Ubiquitination Chromatin Modification Histone Monoubiquitination Histone Ubiquitination Histone Modification Organelle Organization Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Acetylation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Import Intracellular Transport Of Virus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Histone Methylation Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein Ubiquitination RNA Metabolic Process Cellular Protein Modification Process Regulation Of Histone Methylation Histone H4 Acetylation Protein Modification By Small Protein Conjugation Regulation Of Homologous Chromosome Segregation Positive Regulation Of Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Histone Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Meiotic Recombination Checkpoint Positive Regulation Of Vitamin D Receptor Signaling Pathway	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization Chromatin Modification Organ Development Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Signaling Regulation Of Binding Response To Transforming Growth Factor Beta Positive Regulation Of Metabolic Process Cell Cycle Chromosome Organization Negative Regulation Of Cell Differentiation
Tagcloud ?		alters aspect comprise correlating cryptic exonic h2b h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing talk transcribed trimethylation u2	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Difference) ?		alters aspect comprise correlating cryptic exonic h2b h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing talk transcribed trimethylation u2	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Intersection) ?