ZBTB24 and KPNA3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZBTB24	KPNA3
Gene Name		zinc finger and BTB domain containing 24	karyopherin alpha 3 (importin alpha 4)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Pore Nucleoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Protein Transporter Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Complex Assembly NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway Viral Entry Into Host Cell Viral Penetration Into Host Nucleus
Pathways			ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Height ( 20881960 18391951)	Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661)
Protein-Protein Interactions		36 interactors: AES BAX BCL11A BLZF1 CALM1 CCNDBP1 CDA CEP70 CEP76 DNM1L HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LDOC1 MDFI MID2 PHC2 POGZ PRMT7 SSX2IP SUV39H1 TRIM41 TSC22D4 TSGA10 ZBTB43 ZBTB8A	28 interactors: APOL6 CDKN1B COIL DDX21 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 HNRNPC KPNB1 MAT2B MTA1 MVP MYOD1 NFE2L2 NFKB1 NUP50 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131
Entrez ID		9841	3839
HPRD ID		18315	03536
Ensembl ID		ENSG00000112365	ENSG00000102753
Uniprot IDs		O43167	O00505 Q8IYQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Regulation Of Protein Oligomerization Regulation Of Binding Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Mitochondrion Morphogenesis Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Transcription, DNA-templated Organelle Organization Mitochondrial Fission Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Release Of Cytochrome C From Mitochondria Regulation Of RNA Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Assembly Negative Regulation Of DNA Binding Release Of Matrix Enzymes From Mitochondria Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Apoptotic DNA Fragmentation Mitochondrial Membrane Fission B Cell Receptor Apoptotic Signaling Pathway Dynamin Polymerization Involved In Mitochondrial Fission T Cell Homeostatic Proliferation Programmed Necrotic Cell Death Necrotic Cell Death Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mitochondrion Organization RNA Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine B Cell Negative Selection Retinal Cell Apoptotic Process Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Viral Penetration Into Host Nucleus Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Protein Localization To Organelle Protein Homotetramerization	Viral Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Response To Organic Substance Nitrogen Compound Metabolic Process Gene Expression Nucleotide-excision Repair, DNA Damage Removal Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Termination Of RNA Polymerase I Transcription Programmed Cell Death Transcription Elongation From RNA Polymerase I Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process Osteoblast Differentiation Transcription Initiation From RNA Polymerase I Promoter Cell Death Death 7-methylguanosine MRNA Capping Response To Abiotic Stimulus Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Positive Regulation Of Metabolic Process Regulation Of Gene Expression Transcription-coupled Nucleotide-excision Repair Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription Positive Regulation Of Wound Healing Regulation Of Nucleic Acid-templated Transcription Cellular Response To DNA Damage Stimulus Regulation Of RNA Biosynthetic Process Response To Lipid Response To Estrogen Regulation Of Gene Expression, Epigenetic Negative Regulation Of Interleukin-12 Biosynthetic Process Nucleotide-excision Repair, DNA Duplex Unwinding Notochord Cell Development Regulation Of Cell Cycle Process Cellular Macromolecule Catabolic Process Macromolecule Biosynthetic Process
Tagcloud ?			alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Difference) ?			alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Intersection) ?