ZBTB24 and PRMT7

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		ZBTB24	PRMT7
Gene Name		zinc finger and BTB domain containing 24	protein arginine methyltransferase 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)
	Biological Process	Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Height ( 20881960 18391951)	Magnesium levels ( 20700443)
Protein-Protein Interactions		36 interactors: AES BAX BCL11A BLZF1 CALM1 CCNDBP1 CDA CEP70 CEP76 DNM1L HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LDOC1 MDFI MID2 PHC2 POGZ PRMT7 SSX2IP SUV39H1 TRIM41 TSC22D4 TSGA10 ZBTB43 ZBTB8A	10 interactors: CTCFL DIO3 H3F3C HIST1H3A HIST1H4A HIST2H2AC MNDA POT1 SNRPB ZBTB24
Entrez ID		9841	54496
HPRD ID		18315	15174
Ensembl ID		ENSG00000112365	ENSG00000132600
Uniprot IDs		O43167	Q9NVM4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Regulation Of Protein Oligomerization Regulation Of Binding Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Mitochondrion Morphogenesis Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Transcription, DNA-templated Organelle Organization Mitochondrial Fission Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Release Of Cytochrome C From Mitochondria Regulation Of RNA Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Assembly Negative Regulation Of DNA Binding Release Of Matrix Enzymes From Mitochondria Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Apoptotic DNA Fragmentation Mitochondrial Membrane Fission B Cell Receptor Apoptotic Signaling Pathway Dynamin Polymerization Involved In Mitochondrial Fission T Cell Homeostatic Proliferation Programmed Necrotic Cell Death Necrotic Cell Death Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mitochondrion Organization RNA Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine B Cell Negative Selection Retinal Cell Apoptotic Process Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Viral Penetration Into Host Nucleus Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Protein Localization To Organelle Protein Homotetramerization	DNA Methylation DNA Modification DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Cellular Aromatic Compound Metabolic Process Chromatin Silencing Cellular Nitrogen Compound Metabolic Process DNA Conformation Change Nitrogen Compound Metabolic Process Telomere Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of DNA Strand Elongation Chromosome Organization Methylation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Silencing Thyroid Hormone Catabolic Process Heterocycle Metabolic Process Nucleosome Assembly Gene Expression Telomere Formation Via Telomerase Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Cellular Macromolecular Complex Assembly Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Positive Regulation Of Helicase Activity Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase DNA Packaging Chromatin Organization Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Hormone Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Growth Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Component Assembly Regulation Of Telomerase Activity
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