ZBTB24 and BCL11A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZBTB24	BCL11A
Gene Name		zinc finger and BTB domain containing 24	B-cell CLL/lymphoma 11A (zinc finger protein)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Transcription Corepressor Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Protein Sumoylation B Cell Differentiation T Cell Differentiation Negative Regulation Of Axon Extension Negative Regulation Of Protein Homooligomerization Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Collateral Sprouting Positive Regulation Of Collateral Sprouting Regulation Of Dendrite Development Negative Regulation Of Dendrite Development
Pathways
Drugs
Diseases
GWAS		Height ( 20881960 18391951)	Attention deficit hyperactivity disorder ( 22012869) Beta thalassemia/hemoglobin E disease ( 20183929) F-cell distribution ( 21326311 17767159) Fetal hemoglobin levels ( 18245381 20018918) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285) Mean corpuscular volume ( 19862010) Monocyte early outgrowth colony forming units ( 21493818) Red blood cell traits ( 23222517) Sickle cell anemia (haemolysis) ( 23406172) Type 2 diabetes ( 20581827)
Protein-Protein Interactions		36 interactors: AES BAX BCL11A BLZF1 CALM1 CCNDBP1 CDA CEP70 CEP76 DNM1L HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LDOC1 MDFI MID2 PHC2 POGZ PRMT7 SSX2IP SUV39H1 TRIM41 TSC22D4 TSGA10 ZBTB43 ZBTB8A	20 interactors: ACTC1 APP BCL6 CDCA3 CDK4 CDK6 GMCL1P1 LMO1 NCK2 NR2E1 NR2E3 NR2F1 NR2F2 NR2F6 SIRT1 SUMO1 SUMO2 SUMO3 YME1L1 ZBTB24
Entrez ID		9841	53335
HPRD ID		18315	05949
Ensembl ID		ENSG00000112365	ENSG00000119866
Uniprot IDs		O43167	D6W5D9 D9YZV9 Q9H165
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Regulation Of Protein Oligomerization Regulation Of Binding Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Mitochondrion Morphogenesis Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Transcription, DNA-templated Organelle Organization Mitochondrial Fission Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Release Of Cytochrome C From Mitochondria Regulation Of RNA Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Assembly Negative Regulation Of DNA Binding Release Of Matrix Enzymes From Mitochondria Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Apoptotic DNA Fragmentation Mitochondrial Membrane Fission B Cell Receptor Apoptotic Signaling Pathway Dynamin Polymerization Involved In Mitochondrial Fission T Cell Homeostatic Proliferation Programmed Necrotic Cell Death Necrotic Cell Death Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mitochondrion Organization RNA Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine B Cell Negative Selection Retinal Cell Apoptotic Process Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Viral Penetration Into Host Nucleus Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Protein Localization To Organelle Protein Homotetramerization	Positive Regulation Of Cellular Metabolic Process Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Cellular Senescence Positive Regulation Of Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cell Aging Negative Regulation Of Cellular Metabolic Process Cell Differentiation Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Senescence Protein Sumoylation Developmental Process Positive Regulation Of Macromolecule Biosynthetic Process Response To Steroid Hormone Multicellular Organismal Development Generation Of Neurons Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Neurogenesis System Development Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Organ Development Response To Hormone Protein Modification By Small Protein Conjugation Regulation Of Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Differentiation Forebrain Development Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated DNA-templated Transcription, Initiation Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?			beadchip cpgs cues enhancers erythroblasts erythroid erythropoiesis fetal globin happen hbf hemoglobin highlighting humanmethylation illumina maps mendelian methylated methylation methylome moves overlap red repress sickle switch tend thalassemia unanticipated
Tagcloud (Difference) ?			beadchip cpgs cues enhancers erythroblasts erythroid erythropoiesis fetal globin happen hbf hemoglobin highlighting humanmethylation illumina maps mendelian methylated methylation methylome moves overlap red repress sickle switch tend thalassemia unanticipated
Tagcloud (Intersection) ?