CDK1 and E2F1

  • Number of citations of the paper that reports this interaction (PMID 9199321)
  • 29
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vivo, in vitro)

CDK1

E2F1

Gene Name cyclin-dependent kinase 1 E2F transcription factor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 174 interactors: ABL1 AMPH APLP2 AR ARID4A BCL2 BIRC5 BIRC6 BRCA1 BRCA2 BTRC BUB1 CALD1 CCNA1 CCNA2 CCNB1 CCNB2 CCNE1 CCP110 CD8A CDC25A CDC25B CDC25C CDC6 CDCA2 CDCA5 CDK7 CDKN1A CDKN3 CDT1 CEP55 CHAF1B CIITA CKS1B CKS2 CNOT7 CREM CSN2 CSNK2A1 CSNK2B CUX1 CXCR1 DAB2 DCTN6 DNM2 DUT E2F1 ECT2 EEF1D EEF2K EP300 EPN1 ERCC2 EZH2 FANCA FANCC FANCG FBXO5 FEN1 FOXM1 FYN FZR1 GADD45A GADD45B GADD45G GFAP GOLGA2 GORASP1 H1F0 HIST1H1A HIST1H1B HIST1H1D HIST1H2AB HIST1H2BB HIST1H4A HMGA1 HMGA2 HMGB1 HSPA2 HTRA2 IL16 IL3RA ITPR1 JAK3 KAT5 KHDRBS1 KIF11 KIF20B KIF26B KMT2E KRT18 LATS1 LMNA LMNB1 LYN LZTS1 MAP4 MAPT MARCKS MBP MCM4 MDM4 MEF2C MKI67 MLKL MNDA MYC MYT1 NCAPD2 NCAPG NCAPH NCL NDE1 NES NPM1 NSFL1C NUP210 PAK6 PBK PCNA PIN1 PITPNM1 PKMYT1 PLEC PML POLA1 PPP2R1A PPP2R1B PRC1 PTCH1 PTMA PTPN1 PTPN2 PTTG1 RAB4A RAB5B RACGAP1 RAP1GAP RB1 RCC1 RELB REPS2 RGCC RPA1 RPA2 RPS6KB1 RRM2 RUNX1 RUNX2 SFN SP1 SPAG5 SQSTM1 SSBP1 STMN1 STMN2 TFDP1 TGFBR2 TK1 TLE1 TNNC1 TOP2A TP53 TP53BP1 TP73 TSC1 TSPYL2 UBA1 UBE2A UHRF2 USP16 VIM WEE1 ZBTB16 70 interactors: ARID3A ATAD2 ATM ATR BRCA1 BRD2 BTRC CCNA1 CCNA2 CDK1 CDK2 CDK3 CDK7 CDKN2A CEBPE CHEK2 CREBBP CTDP1 CUL1 DDB2 E2F6 ERCC3 FHL2 GSK3B GTF2H1 HCFC1 IGF1 KAT5 KDM1A MDM2 MDM4 MGA MNAT1 MYBL2 NCOA3 NCOA6 NCOR2 NDN NDNL2 NFKB1 NPDC1 NRIP1 PARP1 PHB PKIB PRDM2 PURA RARA RB1 RNF144A SERTAD2 SETD7 SKP2 SP1 SP2 SP3 SP4 SPIB STAT1 STOML1 TBP TEAD3 TFDP1 TFDP2 TOPBP1 TP53 TP53BP1 TRRAP VHL YWHAQ
Entrez ID 983 1869
HPRD ID 00302 01806
Ensembl ID ENSG00000170312 ENSG00000101412
Uniprot IDs B7Z3D6 I6L9I5 P06493 Q01094 Q9BSD8
PDB IDs 1LC9 1H24 1O9K 2AZE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
137cs  abundance  accordingly  alteration  arrested  caffeine  cdk2  checkpoint  constitutively  culturing  cytometry  delayed  diminished  g2  hyperphosphorylation  inactivation  irradiated  irradiation  mcf  monitored  overexpressed  pronounced  qualities  radiation  regard  scl  unchanged  uv  whose 
box  coexpression  consensus  delays  displaying  dp  dps  e2fs  ectopic  emphasizes  exit  heterodimerization  heterodimers  lacks  members  namely  pocket  possesses  possessing  preference  quiescent  refer  shares  suppresses  transactivational  tttcccgc  tttcgcgc  unlike 
Tagcloud (Difference) ?
137cs  abundance  accordingly  alteration  arrested  caffeine  cdk2  checkpoint  constitutively  culturing  cytometry  delayed  diminished  g2  hyperphosphorylation  inactivation  irradiated  irradiation  mcf  monitored  overexpressed  pronounced  qualities  radiation  regard  scl  unchanged  uv  whose 
box  coexpression  consensus  delays  displaying  dp  dps  e2fs  ectopic  emphasizes  exit  heterodimerization  heterodimers  lacks  members  namely  pocket  possesses  possessing  preference  quiescent  refer  shares  suppresses  transactivational  tttcccgc  tttcgcgc  unlike 
Tagcloud (Intersection) ?