TSC22D2 and CLIP1

Number of citations of the paper that reports this interaction (PubMedID 27337956)
0

Data Source:
BioGRID (two hybrid)

		TSC22D2	CLIP1
Description		TSC22 domain family member 2	CAP-Gly domain containing linker protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Kinetochore Ruffle Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Intermediate Filament Plasma Membrane Cell Cortex Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Microtubule Plus-end Cell Projection Macropinosome
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Identical Protein Binding Metal Ion Binding Microtubule Plus-end Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Cell Cycle	Mitotic Cell Cycle Microtubule Bundle Formation Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases activate IQGAPs RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Signaling by LTK in cancer
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32154731 32203549) Type 2 diabetes ( 30297969 30054458) Waist circumference ( 26785701) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	A body shape index ( 34021172) Adiponectin levels ( 31178129) Body fat percentage and HDL-C (pairwise) ( 33619380) Body mass index ( 25673413 26961502) Body mass index and HDL-C (pairwise) ( 33619380) Chronotype ( 30696823) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Walking pace ( 33128006) Weight ( 28552196)
Interacting Genes		43 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 USP7 WNK3 ZMYM2 ZNF143 ZNF251	13 interacting genes: BIN1 CALM1 CLASP2 CLIP4 DCTN1 IQGAP1 MAPRE2 MTOR PAFAH1B1 REL TSC22D2 TUBA1A TUBB
Entrez ID		9819	6249
HPRD ID		11101	01568
Ensembl ID		ENSG00000196428	ENSG00000130779
Uniprot IDs		B4DN36 O75157	B3KXA5 P30622
PDB IDs			2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV 8WHH 8WHI
Enriched GO Terms of Interacting Partners?		Transporter Activator Activity Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Import Across Plasma Membrane Positive Regulation Of Sodium Ion Transport Negative Regulation Of Pancreatic Juice Secretion Regulation Of Potassium Ion Import Regulation Of Sodium Ion Transmembrane Transport Proteasome Core Complex, Alpha-subunit Complex	Microtubule Microtubule Plus-end Binding Cytoskeleton Organization Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Cytoplasmic Microtubule Cell Leading Edge Cell Cortex Cell Division Microtubule Plus-end Microtubule-based Process Regulation Of Cytoskeleton Organization Neuromuscular Process Cytoskeleton Establishment Of Mitotic Spindle Localization Protein-containing Complex Binding Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Epithelial Cell Migration Organelle Assembly Cellular Component Assembly Establishment Of Spindle Localization Cytoskeleton-dependent Intracellular Transport Spindle Localization Organelle Organization Organelle Localization Regulation Of Epithelial Cell Migration Spindle Positive Regulation Of Keratinocyte Migration Microtubule Binding Microtubule Organizing Center Organization Cytoplasmic Ribonucleoprotein Granule Positive Regulation Of Protein Polymerization Regulation Of Microtubule-based Process Establishment Of Organelle Localization Spindle Assembly Establishment Of Localization In Cell Regulation Of Microtubule Polymerization Or Depolymerization Nuclear Membrane Disassembly Regulation Of Synapse Organization Membrane Disassembly Regulation Of Cell Cycle Positive Regulation Of Cellular Component Organization Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Cellular Component Organization Regulation Of Organelle Organization Response To Calcium Ion Mitotic Spindle Microtubule Anchoring Mitotic Cell Cycle Regulation Of Supramolecular Fiber Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?