TOMM20 and TOMM22

Number of citations of the paper that reports this interaction (PMID 10982837)
15

Data Source:
HPRD (in vivo, in vitro)

		TOMM20	TOMM22
Gene Name		translocase of outer mitochondrial membrane 20 homolog (yeast)	translocase of outer mitochondrial membrane 22 homolog (yeast)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Integral Component Of Membrane ER-mitochondrion Membrane Contact Site	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Mitochondrial Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Unfolded Protein Binding	Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Transmembrane Transport	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Import Into Mitochondrial Outer Membrane
Pathways		Mitochondrial protein import	Mitochondrial protein import
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Obesity-related traits ( 23251661)
Protein-Protein Interactions		17 interactors: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 DHFR FEZ1 HAP1 KIAA1377 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	4 interactors: KRTAP5-9 TOMM20 TOMM40 TOMM7
Entrez ID		9804	56993
HPRD ID		03507	06130
Ensembl ID		ENSG00000173726	ENSG00000100216
Uniprot IDs		Q15388	Q549C5 Q9NS69
PDB IDs		4APO
Enriched GO Terms of Interacting Partners?		Mitochondrial Transport Cellular Localization Regulation Of Protein Stability Establishment Of Localization In Cell Developmental Process Anatomical Structure Development Posttranscriptional Regulation Of Gene Expression Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Intracellular Transport Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Learning Mitochondrion Organization Regulation Of Mitotic Cell Cycle Cell Differentiation Cell Cycle Single-organism Behavior Negative Regulation Of Autophagy Response To Organic Cyclic Compound Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Behavioral Fear Response Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Fear Response Protein Localization To Organelle Response To Drug Axon Regeneration Regulation Of Smooth Muscle Cell Migration Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Anion Homeostasis Organ Development Regulation Of Cell Cycle Phase Transition Neuron Projection Regeneration Behavior Organelle Organization Ornithine Catabolic Process Negative Regulation Of Cellular PH Reduction Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cell Adhesion Molecule Production Learning Or Memory Protein Transmembrane Transport System Development Mitochondrial Membrane Organization	Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Establishment Of Protein Localization To Organelle Mitochondrion Organization Protein Targeting Protein Localization To Organelle Cytoplasmic Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Import Into Mitochondrial Matrix Transmembrane Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Intracellular Protein Transmembrane Transport Organelle Organization Cellular Protein Metabolic Process Protein Import Transport Protein Metabolic Process
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