TOMM22 and TOMM20

Number of citations of the paper that reports this interaction (PMID 10982837)
15

Data Source:
HPRD (in vivo, in vitro)

		TOMM22	TOMM20
Gene Name		translocase of outer mitochondrial membrane 22 homolog (yeast)	translocase of outer mitochondrial membrane 20 homolog (yeast)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Mitochondrial Inner Membrane Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Integral Component Of Membrane ER-mitochondrion Membrane Contact Site
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Unfolded Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Import Into Mitochondrial Outer Membrane	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Transmembrane Transport
Pathways		Mitochondrial protein import	Mitochondrial protein import
Drugs
Diseases
GWAS			Cholesterol, total ( 20686565) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: KRTAP5-9 TOMM20 TOMM40 TOMM7	17 interactors: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 DHFR FEZ1 HAP1 KIAA1377 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID		56993	9804
HPRD ID		06130	03507
Ensembl ID		ENSG00000100216	ENSG00000173726
Uniprot IDs		Q549C5 Q9NS69	Q15388
PDB IDs			4APO
Enriched GO Terms of Interacting Partners?		Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Establishment Of Protein Localization To Organelle Mitochondrion Organization Protein Targeting Protein Localization To Organelle Cytoplasmic Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Import Into Mitochondrial Matrix Transmembrane Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Intracellular Protein Transmembrane Transport Organelle Organization Cellular Protein Metabolic Process Protein Import Transport Protein Metabolic Process	Mitochondrial Transport Cellular Localization Regulation Of Protein Stability Establishment Of Localization In Cell Developmental Process Anatomical Structure Development Posttranscriptional Regulation Of Gene Expression Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Intracellular Transport Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Learning Mitochondrion Organization Regulation Of Mitotic Cell Cycle Cell Differentiation Cell Cycle Single-organism Behavior Negative Regulation Of Autophagy Response To Organic Cyclic Compound Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Behavioral Fear Response Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Fear Response Protein Localization To Organelle Response To Drug Axon Regeneration Regulation Of Smooth Muscle Cell Migration Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Anion Homeostasis Organ Development Regulation Of Cell Cycle Phase Transition Neuron Projection Regeneration Behavior Organelle Organization Ornithine Catabolic Process Negative Regulation Of Cellular PH Reduction Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cell Adhesion Molecule Production Learning Or Memory Protein Transmembrane Transport System Development Mitochondrial Membrane Organization
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