TOMM22

Description		translocase of outer mitochondrial membrane 22
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane TOM Complex
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding
	Biological Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Protein Insertion Into Mitochondrial Outer Membrane
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		5 interacting genes: AQP6 HSD17B10 KRTAP5-9 TOMM20 TOMM7
Entrez ID		56993
HPRD ID		06130
Ensembl ID		ENSG00000100216
Uniprot IDs		Q549C5 Q9NS69
PDB IDs		7CK6 7CP9 7VBY 7VC4 7VD2 7VDD 8XVA 9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Mitochondrial Outer Membrane Translocase Complex TOM Complex Protein Insertion Into Mitochondrial Outer Membrane Protein Import Into Mitochondrial Matrix Protein Transmembrane Transporter Activity Mitochondrion Organization Establishment Of Protein Localization To Mitochondrial Membrane Protein Insertion Into Mitochondrial Membrane Protein Localization To Mitochondrion Protein Insertion Into Membrane Nitrate Transmembrane Transporter Activity Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Protein Transmembrane Transport Establishment Of Protein Localization To Mitochondrion Protein-transporting ATPase Activity Mitochondrial Membrane Organization PH-gated Chloride Channel Activity Nitrate Transmembrane Transport 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Brexanolone Metabolic Process TRNA Import Into Mitochondrion Mitochondrial Ribonuclease P Complex Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing Mitochondrial TRNA Methylation Mitochondrial RNA 5'-end Processing Migrasome Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Isoleucine Metabolic Process L-isoleucine Catabolic Process RNA Import Into Mitochondrion Establishment Of Protein Localization To Membrane Mitochondrion Targeting Sequence Binding Mitochondrial Outer Membrane TRNA Methyltransferase Complex Mitochondrial RNA 3'-end Processing Testosterone Dehydrogenase (NAD+) Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity TRNA Transport Androstan-3-alpha,17-beta-diol Dehydrogenase (NAD+) Activity Monoatomic Anion Channel Activity Renal Water Transport TRNA 3'-end Processing Transmembrane Transport Ammonium Channel Activity
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