TOMM20 and OTC

Number of citations of the paper that reports this interaction (PMID 9756929)
6

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TOMM20	OTC
Gene Name		translocase of outer mitochondrial membrane 20 homolog (yeast)	ornithine carbamoyltransferase
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Integral Component Of Membrane ER-mitochondrion Membrane Contact Site	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Unfolded Protein Binding	Ornithine Carbamoyltransferase Activity Phospholipid Binding Amino Acid Binding Phosphate Ion Binding
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Transmembrane Transport	Urea Cycle Liver Development Ornithine Catabolic Process Midgut Development Response To Zinc Ion Citrulline Biosynthetic Process Response To Insulin Cellular Nitrogen Compound Metabolic Process Arginine Biosynthetic Process Via Ornithine Response To Drug Small Molecule Metabolic Process Protein Homotrimerization Response To Biotin Ammonia Homeostasis
Pathways		Mitochondrial protein import	Urea cycle Metabolism of amino acids and derivatives
Drugs			L-Ornithine L-Citrulline N-(Phosphonoacetyl)-L-Ornithine 2-Amino-Pentanoic Acid Norvaline
Diseases
GWAS		Cholesterol, total ( 20686565) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Obesity-related traits ( 23251661)
Protein-Protein Interactions		17 interactors: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 DHFR FEZ1 HAP1 KIAA1377 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	1 interactors: TOMM20
Entrez ID		9804	5009
HPRD ID		03507	08947
Ensembl ID		ENSG00000173726	ENSG00000036473
Uniprot IDs		Q15388	P00480
PDB IDs		4APO	1C9Y 1EP9 1FVO 1OTH
Enriched GO Terms of Interacting Partners?		Mitochondrial Transport Cellular Localization Regulation Of Protein Stability Establishment Of Localization In Cell Developmental Process Anatomical Structure Development Posttranscriptional Regulation Of Gene Expression Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Intracellular Transport Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Learning Mitochondrion Organization Regulation Of Mitotic Cell Cycle Cell Differentiation Cell Cycle Single-organism Behavior Negative Regulation Of Autophagy Response To Organic Cyclic Compound Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Behavioral Fear Response Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Fear Response Protein Localization To Organelle Response To Drug Axon Regeneration Regulation Of Smooth Muscle Cell Migration Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Anion Homeostasis Organ Development Regulation Of Cell Cycle Phase Transition Neuron Projection Regeneration Behavior Organelle Organization Ornithine Catabolic Process Negative Regulation Of Cellular PH Reduction Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cell Adhesion Molecule Production Learning Or Memory Protein Transmembrane Transport System Development Mitochondrial Membrane Organization	Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport
Tagcloud ?			acad authenticity chelators compete cpn60 edta frugiperda genuine hendrick import insect kalousek mdh mncl2 natl organelle ornithine peptidase phenanthroline prechaperonin premalate preornithine preproteins presequence proc proposition rosenberg spodoptora transcarbamylase
Tagcloud (Difference) ?			acad authenticity chelators compete cpn60 edta frugiperda genuine hendrick import insect kalousek mdh mncl2 natl organelle ornithine peptidase phenanthroline prechaperonin premalate preornithine preproteins presequence proc proposition rosenberg spodoptora transcarbamylase
Tagcloud (Intersection) ?