Gene Name |
translocase of outer mitochondrial membrane 20 homolog (yeast) |
dihydrofolate reductase |
Image |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- NADH
- Pyrimethamine
- Trimethoprim
- Methotrexate
- Pemetrexed
- Proguanil
- Trimetrexate
- 2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine
- 2,4-Diamino-6-[N-(2\',5\'-Dimethoxybenzyl)-N-Methylamino]Quinazoline
- 6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine
- N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine
- 2,4-Diamino-6-[N-(3\',4\',5\'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
- Sri-9662
- 2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium
- Sri-9439
- 2\'-Monophosphoadenosine 5\'-Diphosphoribose
- 6-(2,5-Dimethoxy-Benzyl)-5-Methyl-Pyrido[2,3-D]Pyrimidine-2,4-Diamine
- Biopterin
- 2,4-Diamino-6-[N-(3\',5\'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
- Pralatrexate
- 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-4\'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-3\',5\'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-2\',6\'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
- [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
- (4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol
- (2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine
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Diseases |
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GWAS |
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Protein-Protein Interactions |
17 interactors:
AIP
APOA1
ATXN1
BAG6
BCL2
CDC73
DHFR
FEZ1
HAP1
KIAA1377
OTC
PPHLN1
PTN
TOMM22
TOMM40
UCP1
VDAC1
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10 interactors:
AMFR
ASGR1
FKBP1A
GKAP1
HSPD1
MDM2
THBS1
TOMM20
TP53
UBC
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Entrez ID |
9804 |
1719 |
HPRD ID |
03507 |
00519 |
Ensembl ID |
ENSG00000173726
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ENSG00000228716
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Uniprot IDs |
Q15388
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B0YJ76
B4DDD2
P00374
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PDB IDs |
4APO
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1BOZ
1DHF
1DLR
1DLS
1DRF
1HFP
1HFQ
1HFR
1KMS
1KMV
1MVS
1MVT
1OHJ
1OHK
1PD8
1PD9
1PDB
1S3U
1S3V
1S3W
1U71
1U72
1YHO
2C2S
2C2T
2DHF
2W3A
2W3B
2W3M
3EIG
3F8Y
3F8Z
3F91
3FS6
3GHC
3GHV
3GHW
3GI2
3GYF
3L3R
3N0H
3NTZ
3NU0
3NXO
3NXR
3NXT
3NXV
3NXX
3NXY
3NZD
3OAF
3S3V
3S7A
4DDR
4M6J
4M6K
4M6L
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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attains
becomes
charged
combine
crossed
dehydrofolate
evolutionarily
export
import
imported
inner
inserted
intermembrane
lengths
moieties
oxa1p
pairwise
peptidase
polytopic
postulate
poxa1p
preproteins
presequence
segments
sorting
stop
stretches
tm
translocated
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Tagcloud (Difference) ? |
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attains
becomes
charged
combine
crossed
dehydrofolate
evolutionarily
export
import
imported
inner
inserted
intermembrane
lengths
moieties
oxa1p
pairwise
peptidase
polytopic
postulate
poxa1p
preproteins
presequence
segments
sorting
stop
stretches
tm
translocated
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Tagcloud (Intersection) ? |
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