OTC and TOMM20

Number of citations of the paper that reports this interaction (PMID 9756929)
6

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		OTC	TOMM20
Gene Name		ornithine carbamoyltransferase	translocase of outer mitochondrial membrane 20 homolog (yeast)
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Mitochondrion Mitochondrial Outer Membrane Translocase Complex Integral Component Of Membrane ER-mitochondrion Membrane Contact Site
	Molecular Function	Ornithine Carbamoyltransferase Activity Phospholipid Binding Amino Acid Binding Phosphate Ion Binding	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Unfolded Protein Binding
	Biological Process	Urea Cycle Liver Development Ornithine Catabolic Process Midgut Development Response To Zinc Ion Citrulline Biosynthetic Process Response To Insulin Cellular Nitrogen Compound Metabolic Process Arginine Biosynthetic Process Via Ornithine Response To Drug Small Molecule Metabolic Process Protein Homotrimerization Response To Biotin Ammonia Homeostasis	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Transmembrane Transport
Pathways		Urea cycle Metabolism of amino acids and derivatives	Mitochondrial protein import
Drugs		L-Ornithine L-Citrulline N-(Phosphonoacetyl)-L-Ornithine 2-Amino-Pentanoic Acid Norvaline
Diseases
GWAS			Cholesterol, total ( 20686565) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Obesity-related traits ( 23251661)
Protein-Protein Interactions		1 interactors: TOMM20	17 interactors: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 DHFR FEZ1 HAP1 KIAA1377 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID		5009	9804
HPRD ID		08947	03507
Ensembl ID		ENSG00000036473	ENSG00000173726
Uniprot IDs		P00480	Q15388
PDB IDs		1C9Y 1EP9 1FVO 1OTH	4APO
Enriched GO Terms of Interacting Partners?		Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport	Mitochondrial Transport Cellular Localization Regulation Of Protein Stability Establishment Of Localization In Cell Developmental Process Anatomical Structure Development Posttranscriptional Regulation Of Gene Expression Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Intracellular Transport Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Learning Mitochondrion Organization Regulation Of Mitotic Cell Cycle Cell Differentiation Cell Cycle Single-organism Behavior Negative Regulation Of Autophagy Response To Organic Cyclic Compound Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Behavioral Fear Response Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Fear Response Protein Localization To Organelle Response To Drug Axon Regeneration Regulation Of Smooth Muscle Cell Migration Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Anion Homeostasis Organ Development Regulation Of Cell Cycle Phase Transition Neuron Projection Regeneration Behavior Organelle Organization Ornithine Catabolic Process Negative Regulation Of Cellular PH Reduction Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cell Adhesion Molecule Production Learning Or Memory Protein Transmembrane Transport System Development Mitochondrial Membrane Organization
Tagcloud ?		acad authenticity chelators compete cpn60 edta frugiperda genuine hendrick import insect kalousek mdh mncl2 natl organelle ornithine peptidase phenanthroline prechaperonin premalate preornithine preproteins presequence proc proposition rosenberg spodoptora transcarbamylase
Tagcloud (Difference) ?		acad authenticity chelators compete cpn60 edta frugiperda genuine hendrick import insect kalousek mdh mncl2 natl organelle ornithine peptidase phenanthroline prechaperonin premalate preornithine preproteins presequence proc proposition rosenberg spodoptora transcarbamylase
Tagcloud (Intersection) ?