KIAA0408 and BEGAIN

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		KIAA0408	BEGAIN
Description		KIAA0408	brain enriched guanylate kinase associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Membrane Synapse Postsynapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Evoked Excitatory Postsynaptic Potential
Pathways			Neurexins and neuroligins
Drugs
Diseases
GWAS		Asthma ( 31959851) Hip index ( 34021172) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		42 interacting genes: ABI1 ABI3 AP2B1 BEGAIN CARD9 CBY2 CCDC57 CCDC85B CEP72 DCTN1 DTNBP1 FRS3 GFAP GRB2 HOOK2 HSF2BP KDM1A KRT15 MAGEA11 MDFI MYO15B NCK2 NDOR1 PFDN1 PHF1 PIK3R3 POLR3C PRMT6 RUNX1T1 SFN SORBS3 TEX11 TLE1 TRAF2 TRIM37 TRIM55 TRIM63 UBASH3A VIM XRCC6 YWHAG ZDHHC17	47 interacting genes: ABLIM1 APP AQP1 ATPAF2 BAHD1 BMP7 CATSPER1 CDC23 DDX6 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A FAM161A FAM90A1 GEM GFI1B GMCL1 GUCD1 HDAC4 HGS HID1 KIAA0408 KIFC3 LENG1 MAB21L3 PRPF18 PRR35 QSOX1 RASAL3 RBL1 RIBC2 SAXO1 TRAF4 TRIM27 USP2 ZFP64 ZNF250 ZNF319 ZNF417 ZNF572 ZNF587 ZNF648 ZNF774 ZNF835
Entrez ID		9729	57596
HPRD ID		17187	06459
Ensembl ID		ENSG00000189367	ENSG00000183092
Uniprot IDs		Q6ZU52	A0A1B0GTT1 G3V3A2 G3V3R5 Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Signaling Adaptor Activity Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Cytoskeleton Organization Protein Kinase C Inhibitor Activity Cytoplasm Scaffold Protein Binding IRE1-TRAF2-ASK1 Complex Regulation Of Cellular Component Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Vesicle Membrane Structural Constituent Of Cytoskeleton Regulation Of Metabolic Process Innate Immune Response Protein Sequestering Activity Actin-based Cell Projection Negative Regulation Of Metabolic Process Phosphotyrosine Residue Binding Organelle Organization Intermediate Filament Cytoskeleton Negative Regulation Of Macromolecule Metabolic Process Bergmann Glial Cell Differentiation Regulation Of Protein Kinase Activity Regulation Of Macromolecule Metabolic Process SCAR Complex Cellular Response To Stress Protein Binding Regulation Of Kinase Activity Cell Leading Edge Defense Response To Symbiont Regulation Of JNK Cascade Defense Response To Other Organism Glial Cell Development ESC/E(Z) Complex Negative Regulation Of Macromolecule Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Cytoskeleton Regulation Of Gene Expression Cellular Response To Ionizing Radiation Intermediate Filament Organization Cellular Response To Reactive Nitrogen Species Negative Regulation Of Biosynthetic Process Positive Regulation Of Supramolecular Fiber Organization Astrocyte Development Regulation Of Intracellular Signal Transduction Regulation Of Protein Metabolic Process Negative Regulation Of Anoikis	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Zinc Ion Binding NMDA Selective Glutamate Receptor Signaling Pathway Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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