KIAA0408 and CEP72

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		KIAA0408	CEP72
Gene Name		KIAA0408	centrosomal protein 72kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Centrosome Cytosol
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spindle Organization Gamma-tubulin Complex Localization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Ulcerative colitis ( 20228799)
Protein-Protein Interactions		26 interactors: ABI3 AP2B1 BEGAIN CARD9 CCDC85B CEP72 DCTN1 DTNBP1 GFAP HOOK2 KDM1A KRT15 MAGEA11 MDFI PFDN1 PRMT6 SFN SORBS3 TEX11 TLE1 TRAF2 TRIM37 VIM XRCC6 YWHAG ZDHHC17	17 interactors: ATXN7 CATIP FAM90A1 IGHM KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417
Entrez ID		9729	55722
HPRD ID		17187	07685
Ensembl ID			ENSG00000112877
Uniprot IDs		Q6ZU52	Q9P209
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Bergmann Glial Cell Differentiation Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction Developmental Process System Development Anatomical Structure Development Intermediate Filament Organization Positive Regulation Of Signal Transduction Astrocyte Development G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of JNK Cascade Nervous System Development Multicellular Organismal Development Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Process Regulation Of Apoptotic Process Regulation Of Cellular Component Organization Regulation Of Phosphorus Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of JNK Cascade Cellular Response To Stress Regulation Of Metabolic Process Regulation Of Cell Death Intermediate Filament Cytoskeleton Organization Regulation Of Protein Kinase Activity Cytoskeleton Organization Regulation Of Cell Differentiation Astrocyte Differentiation Protein Autoubiquitination Regulation Of Stress-activated MAPK Cascade Intermediate Filament-based Process Negative Regulation Of DNA Binding Positive Regulation Of MAPK Cascade Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Schwann Cell Proliferation Positive Regulation Of Intracellular Signal Transduction	Intraciliary Transport Cilium Organization Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
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