KIAA0408 and CEP72

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		KIAA0408	CEP72
Description		KIAA0408	centrosomal protein 72
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Centrosome Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Spindle Organization Centriole Replication Gamma-tubulin Complex Localization Regulation Of Protein Localization To Centrosome
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Asthma ( 31959851) Hip index ( 34021172) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Esophageal adenocarcinoma ( 27527254) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Ulcerative colitis ( 20228799 28067908) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658)
Interacting Genes		42 interacting genes: ABI1 ABI3 AP2B1 BEGAIN CARD9 CBY2 CCDC57 CCDC85B CEP72 DCTN1 DTNBP1 FRS3 GFAP GRB2 HOOK2 HSF2BP KDM1A KRT15 MAGEA11 MDFI MYO15B NCK2 NDOR1 PFDN1 PHF1 PIK3R3 POLR3C PRMT6 RUNX1T1 SFN SORBS3 TEX11 TLE1 TRAF2 TRIM37 TRIM55 TRIM63 UBASH3A VIM XRCC6 YWHAG ZDHHC17	26 interacting genes: ATXN7 CATIP CHCHD3 FAM161A FAM90A1 FXR1 GOLGA6L9 IGHM IL16 INCA1 KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SHANK3 SMARCA2 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417 ZNF688
Entrez ID		9729	55722
HPRD ID		17187	07685
Ensembl ID		ENSG00000189367	ENSG00000112877
Uniprot IDs		Q6ZU52	Q9P209
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Signaling Adaptor Activity Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Cytoskeleton Organization Protein Kinase C Inhibitor Activity Cytoplasm Scaffold Protein Binding IRE1-TRAF2-ASK1 Complex Regulation Of Cellular Component Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Vesicle Membrane Structural Constituent Of Cytoskeleton Regulation Of Metabolic Process Innate Immune Response Protein Sequestering Activity Actin-based Cell Projection Negative Regulation Of Metabolic Process Phosphotyrosine Residue Binding Organelle Organization Intermediate Filament Cytoskeleton Negative Regulation Of Macromolecule Metabolic Process Bergmann Glial Cell Differentiation Regulation Of Protein Kinase Activity Regulation Of Macromolecule Metabolic Process SCAR Complex Cellular Response To Stress Protein Binding Regulation Of Kinase Activity Cell Leading Edge Defense Response To Symbiont Regulation Of JNK Cascade Defense Response To Other Organism Glial Cell Development ESC/E(Z) Complex Negative Regulation Of Macromolecule Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Cytoskeleton Regulation Of Gene Expression Cellular Response To Ionizing Radiation Intermediate Filament Organization Cellular Response To Reactive Nitrogen Species Negative Regulation Of Biosynthetic Process Positive Regulation Of Supramolecular Fiber Organization Astrocyte Development Regulation Of Intracellular Signal Transduction Regulation Of Protein Metabolic Process Negative Regulation Of Anoikis
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