NUP93 and GRSF1

Number of citations of the paper that reports this interaction (PubMedID 32645484)
0

Data Source:
BioGRID (two hybrid)

		NUP93	GRSF1
Description		nucleoporin 93	G-rich RNA sequence binding factor 1
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Centrosome Cytosol Membrane Nuclear Membrane Nuclear Periphery	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid Ribonucleoprotein Complex
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	G-quadruplex RNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Envelope Organization Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Positive Regulation Of SMAD Protein Signal Transduction	Mitochondrial RNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process MRNA Processing TRNA Processing Anterior/posterior Pattern Specification Morphogenesis Of Embryonic Epithelium Regulation Of RNA Splicing
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses	Viral mRNA Translation Mitochondrial RNA degradation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Gambling ( 22780124) HDL cholesterol ( 20031564) HDL cholesterol levels ( 26763881 32203549) Potassium levels ( 29403010)	Type 2 diabetes ( 30718926)
Interacting Genes		10 interacting genes: AP5Z1 CEBPA GRSF1 MPPED2 NDC1 NUP205 NUP35 OPCML PLA2G6 TMEM100	55 interacting genes: AUP1 BTBD6 CNRIP1 COMMD1 CYC1 DACT1 EIF1B ERO1A FADS2 FNTA FYN GSE1 GTF2E2 HCFC2 HIVEP3 ISYNA1 MAP6 MIR1-2 MIR106B MIR18B MIR200B MIR200C MIR205 MIR25 MIR31 MIR451A MIR9-1 MIR9-2 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEUROD2 NOP53 NUP153 NUP93 OGT PIN1 PPIA PRNP PSMD10 RAB3A RING1 SLC25A21-AS1 UBE3C VPS11 ZNF3
Entrez ID		9688	2926
HPRD ID		14854	07276
Ensembl ID		ENSG00000102900	ENSG00000132463
Uniprot IDs		Q8N1F7	Q12849
PDB IDs		5IJN 5IJO 7MW0 7MW1 7PER 7R5J 7R5K	2LMI 4QU6 4QU7
Enriched GO Terms of Interacting Partners?		Nuclear Pore Organization Structural Constituent Of Nuclear Pore Nucleus Organization Nuclear Pore Complex Assembly Nuclear Pore Pore Complex Assembly MRNA Transport RNA Transport Nucleobase-containing Compound Transport Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Nuclear Membrane RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Nuclear Pore Transmembrane Ring Response To Vitamin B2 C/EBP Complex AP-5 Adaptor Complex GMP Binding CHOP-C/EBP Complex Positive Regulation Of Mitochondrial RNA Catabolic Process Nuclear Pore Inner Ring Notch Signaling Pathway White Fat Cell Proliferation Phosphatidylethanolamine Catabolic Process Protein Transport Arterial Endothelial Cell Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Cardiolipin Acyl-chain Remodeling AP-type Membrane Coat Adaptor Complex Nuclear Pore Localization	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Translation MRNA Destabilization Negative Regulation Of Protein Metabolic Process RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of MRNA Stability Positive Regulation Of Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development
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