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MORF4L2 and KLHL3
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
MORF4L2
KLHL3
Gene Name
mortality factor 4 like 2
kelch-like family member 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytosol
Cytoskeleton
Cul3-RING Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Actin Binding
Structural Molecule Activity
Protein Binding
Biological Process
DNA Repair
Chromatin Organization
Transcription, DNA-templated
Chromatin Modification
Regulation Of Growth
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Striated Muscle Cell Differentiation
Protein Ubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Ion Homeostasis
Renal Sodium Ion Absorption
Protein K48-linked Ubiquitination
Distal Tubule Morphogenesis
Pathways
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions
28 interactors:
AES
BEND7
CDR2
CEP55
DDIT4L
FAM9B
GOLGA2
GRAMD3
HDAC1
IKZF1
KLHL3
L3MBTL3
LZTS2
MRFAP1
MRFAP1L1
MRGBP
PHC2
PNMA2
RB1
SIN3A
THAP1
TLE1
TNIP1
TNNT2
ZBTB10
ZBTB14
ZBTB43
ZBTB7B
12 interactors:
C6orf165
CUL3
GNAI1
GNAO1
KEAP1
KLHL12
MORF4L2
OPRD1
SYNCRIP
SYT2
WNK3
WNK4
Entrez ID
9643
26249
HPRD ID
02326
09011
Ensembl ID
ENSG00000123562
ENSG00000146021
Uniprot IDs
Q15014
Q9UH77
PDB IDs
4HXI
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Biosynthetic Process
Chromatin Modification
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Chromatin Organization
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Signaling
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Binding
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Anoikis
Organ Development
Cell Cycle
Chromosome Organization
Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Mitotic Cell Cycle
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neutrophil Differentiation
Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Response To Methylglyoxal
Negative Regulation Of Histone H3-K27 Acetylation
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Myeloid Leukocyte Differentiation
Positive Regulation Of Cell Cycle Phase Transition
Developmental Process
Negative Regulation Of Protein Binding
Histone Deacetylation
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Cellular Response To Stimulus
COPII Vesicle Coating
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
COPII-coated Vesicle Budding
Regulation Of Calcium Ion Transport
Vesicle Targeting, To, From Or Within Golgi
Vesicle Organization
Protein Monoubiquitination
Localization Within Membrane
Vesicle Targeting
Response To Stimulus
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Rubidium Ion Transport
Positive Regulation Of Rubidium Ion Transmembrane Transporter Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Membrane Budding
ER To Golgi Vesicle-mediated Transport
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Distal Tubule Morphogenesis
Trophectodermal Cellular Morphogenesis
Positive Regulation Of Protein Metabolic Process
Renal Sodium Ion Absorption
Proteasomal Ubiquitin-independent Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Protein Ubiquitination
Positive Regulation Of Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Pancreatic Juice Secretion
Renal Sodium Ion Transport
CRD-mediated MRNA Stabilization
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation
Regulation Of Rubidium Ion Transport
Protein Modification By Small Protein Conjugation
Regulation Of Ion Transport
Cytoplasmic Transport
Signal Transduction
Response To Organic Substance
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Wnt Signaling Pathway
Response To Cytokine
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Establishment Of Vesicle Localization
Vesicle Localization
Tagcloud
?
aii
cotransporter
cul3
cullin
depletion
directing
hyperkalemia
hypertension
impair
inverse
kelch
ligase
maximize
maximized
missense
nacl
obligatory
obscure
phenocopy
physiologic
posited
prevents
reabsorption
s433
salt
volume
wnk1
wnk4
wnks
Tagcloud (Difference)
?
aii
cotransporter
cul3
cullin
depletion
directing
hyperkalemia
hypertension
impair
inverse
kelch
ligase
maximize
maximized
missense
nacl
obligatory
obscure
phenocopy
physiologic
posited
prevents
reabsorption
s433
salt
volume
wnk1
wnk4
wnks
Tagcloud (Intersection)
?