MORF4L2 and GPBP1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		MORF4L2	GPBP1
Name		mortality factor 4 like 2	GC-rich promoter binding protein 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding	DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding
	Biological Process	DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	DNA-templated Transcription Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	None
GWAS		Lymphocyte percentage of white cells ( 32888494 ) Mean platelet volume ( 32888494 )	Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 33768542 ) Diastolic blood pressure ( 27841878 ) Nontraumatic osteonecrosis of the femoral head ( 32701715 ) Normal facial asymmetry (angle of deformation score) ( 30631343 ) Zinc levels ( 26025379 )
Novel Interactors		1 novel interactors: GLA	None recorded
Interacting Genes		54 interacting genes: AMOTL2 ARID3A BCL11A BEND7 BEX5 CAMK2B CDR2 CEP55 DDIT4L DISC1 DSCAM EVI5 FAM9B FBXO16 GOLGA2 GPBP1 GRAMD2B HDAC1 HMBOX1 HOMEZ HUNK IKZF1 KCTD1 KLHL3 L3MBTL3 LUZP4 LZTS2 MEOX2 MRFAP1 MRGBP MRPL12 NAB2 PHC2 PIBF1 PICK1 PNMA2 POU6F2 RB1 REL SIN3A SYN3 THAP1 TLE1 TLE5 TNIP1 TNNT2 TRIM41 TSN ZBTB10 ZBTB14 ZBTB26 ZBTB43 ZBTB7B ZNF48	15 interacting genes: CCDC57 DNAL4 EP300 FAM161A FNDC11 HSF2BP MCRS1 MORF4L2 NXF1 PLEKHF2 PRPF18 PSMB1 QARS1 RACK1 TSC22D2
Entrez ID		9643	65056
HPRD ID		02326	16333
Ensembl ID		ENSG00000123562	ENSG00000062194
Uniprot IDs		Q15014	D4PHA4 Q86WP2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Corepressor Activity Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Nucleoplasm Regulation Of Axon Extension RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Importin-alpha Family Protein Binding Positive Regulation Of Cell Development Positive Regulation Of Neurogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Neurogenesis	None