BORA and FEZ1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BORA	FEZ1
Description		BORA aurora kinase A activator	fasciculation and elongation protein zeta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Meiotic Spindle	Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Microtubule Plasma Membrane Membrane Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding
	Biological Process	Regulation Of Mitotic Nuclear Division Regulation Of Protein Localization Cell Division Regulation Of Mitotic Spindle Organization	Mitochondrion Organization Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Cyclin A/B1/B2 associated events during G2/M transition
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		5 interacting genes: AURKA BTRC CRYAA FEZ1 FGFR3	60 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 DYRK1A FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 NRIP1 OLFML3 P4HB PAM16 PCNT PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		79866	9638
HPRD ID		13389	09212
Ensembl ID		ENSG00000136122	ENSG00000149557
Uniprot IDs		A0A087WV86 B5LMG6 Q6PGQ7	Q99689
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Death Apoptotic Process Lens Fiber Cell Morphogenesis Regulation Of Intracellular Transport Regulation Of Protein Stability Mitochondrion Organization Programmed Cell Death Developmental Process Positive Regulation Of Protein Metabolic Process Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Positive Regulation Of Phospholipase Activity Bone Maturation Positive Regulation Of Lipase Activity Fibroblast Growth Factor Receptor Activity Positive Regulation Of Proteolysis Regulation Of Microtubule-based Process Spindle Assembly Involved In Female Meiosis I Regulation Of Proteasomal Protein Catabolic Process Pronucleus Germinal Vesicle Chromosome Passenger Complex Positive Regulation Of Cell Maturation Mitotic Centrosome Separation Histone H3S10 Kinase Activity Axon Hillock Positive Regulation Of Oocyte Maturation Negative Regulation Of Autophagy Protein Phosphorylated Amino Acid Binding Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Endochondral Bone Growth Regulation Of Organelle Transport Along Microtubule Tubulin Complex Assembly Negative Regulation Of Metabolic Process Response To UV-A Animal Organ Development Embryonic Camera-type Eye Morphogenesis Regulation Of Metabolic Process Lens Morphogenesis In Camera-type Eye Chondrocyte Proliferation Developmental Growth Bone Growth Meiotic Spindle Cilium Disassembly Centrosome Separation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Microtubule Spindle Assembly Involved In Female Meiosis Meiotic Spindle Assembly	Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Autophagosome Microtubule Cytoskeleton Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Response To Stress Centrosome Regulation Of Macroautophagy Microtubule Cytoskeleton Organization Involved In Mitosis Microtubule-based Process Positive Regulation Of Protein Lipidation Cytoskeleton Regulation Of Endoplasmic Reticulum Tubular Network Organization RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of Protein Lipidation Regulation Of Organelle Assembly Regulation Of Microtubule-based Process RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Macroautophagy Positive Regulation Of Organelle Assembly Regulation Of Autophagy Microtubule Organizing Center Mitotic Spindle Organization Axon Negative Regulation Of Microtubule Polymerization Or Depolymerization Chondroitin Sulfate Binding Regulation Of Autophagosome Assembly Regulation Of Organelle Organization
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