AATK and STK39

Number of citations of the paper that reports this interaction (PMID 14563843)
47

Data Source:
BioGRID (two hybrid)

		AATK	STK39
Gene Name		apoptosis-associated tyrosine kinase	serine threonine kinase 39
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Axonal Growth Cone Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Cytoplasm Cytoskeleton Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding
	Biological Process	Brain Development Negative Regulation Of Axon Extension Rab Protein Signal Transduction Peptidyl-tyrosine Autophosphorylation Neuron Apoptotic Process	Protein Phosphorylation Response To Stress Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Signal Transduction By Phosphorylation Intracellular Signal Transduction Positive Regulation Of Potassium Ion Transport Regulation Of Inflammatory Response Cellular Hypotonic Response Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Rubidium Ion Transport Negative Regulation Of Rubidium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Blood pressure ( 19114657) Parkinson's disease ( 21292315)
Protein-Protein Interactions		3 interactors: PPP1CA PPP1CC STK39	13 interactors: AATK GSN HSPH1 MAPK14 MBP OTOF PRKCQ RELT SLC12A1 SLC12A2 SLC12A6 SPP1 WNK4
Entrez ID		9625	27347
HPRD ID		05591	09627
Ensembl ID		ENSG00000181409	ENSG00000198648
Uniprot IDs		H7C175 Q6ZMQ8	Q9UEW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Triglyceride Metabolic Process Regulation Of Circadian Rhythm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Energy Reserve Metabolic Process Response To Abiotic Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Circadian Rhythm Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cellular Carbohydrate Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Lipid Catabolic Process Protein Dephosphorylation Negative Regulation Of Rubidium Ion Transport Negative Regulation Of Rubidium Ion Transmembrane Transporter Activity Energy Derivation By Oxidation Of Organic Compounds Rhythmic Process Regulation Of Rubidium Ion Transport Response To Light Stimulus Glycerolipid Metabolic Process Generation Of Precursor Metabolites And Energy Cell Division Response To Radiation Regulation Of Glycogen Catabolic Process Dephosphorylation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Growth Factor Stimulus Phosphate-containing Compound Metabolic Process Cellular Hypotonic Response Response To Growth Factor Hypotonic Response Cellular Protein Modification Process Negative Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport	Chloride Transport System Development Negative Regulation Of Axonogenesis Multicellular Organismal Development Inorganic Anion Transport Anatomical Structure Development Negative Regulation Of Cell Morphogenesis Involved In Differentiation Developmental Process Chloride Transmembrane Transport Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Response To Stress Regulation Of Axonogenesis Positive Regulation Of Interleukin-4 Production Negative Regulation Of Neuron Differentiation Regulation Of Interleukin-4 Production Response To External Stimulus Potassium Ion Transport Regulation Of Cellular Component Organization Regulation Of Cell Adhesion Organ Development Anion Transport Monovalent Inorganic Cation Transport Sodium Ion Transport Tissue Regeneration Developmental Growth Negative Regulation Of Neurogenesis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Aging Regulation Of Cellular Component Size Negative Regulation Of Cell Development Positive Regulation Of Cell Volume Rubidium Ion Transport Cellular Hypotonic Salinity Response Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury P38MAPK Cascade Anatomical Structure Morphogenesis Metal Ion Transport Regulation Of Cell Growth Execution Phase Of Apoptosis Response To Stimulus Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Response To Osmotic Stress Neurogenesis Negative Regulation Of Developmental Growth Anion Transmembrane Transport Tissue Development Positive Regulation Of T-helper 2 Cell Activation Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Tagcloud ?			atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb nt5c2 overlapped pharmacogenomics plcd3 plekha7 sh2b3 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Difference) ?			atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb nt5c2 overlapped pharmacogenomics plcd3 plekha7 sh2b3 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Intersection) ?