TCL1B and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		TCL1B	TNPO2
Description		TCL1 family AKT coactivator B	transportin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Intracellular Signal Transduction	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Negative Regulation Of Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		17 interacting genes: AKT1 AKT2 APP BAG4 DRC8 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330	54 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CEBPA CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RBM45 REDIC1 RIPK4 RNF10 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		9623	30000
HPRD ID		04795	04301
Ensembl ID		ENSG00000213231	ENSG00000105576
Uniprot IDs		O95988	O14787 Q05D48
PDB IDs
Enriched GO Terms of Interacting Partners?		Lsm1-7-Pat1 Complex Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane U4/U6 X U5 Tri-snRNP Complex Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex U6 SnRNP RNA Splicing, Via Transesterification Reactions Negative Regulation Of PERK-mediated Unfolded Protein Response Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Fibroblast Migration U2-type Prespliceosome Nucleus Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Polysaccharide Biosynthetic Process MRNA Catabolic Process Molecular Function Activator Activity U12-type Spliceosomal Complex Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Postsynapse Organization RNA Binding RNA Splicing Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Oxidation Positive Regulation Of Small Molecule Metabolic Process Negative Regulation Of Gene Expression Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Protein Localization To Plasma Membrane Regulation Of Fibroblast Migration Response To Nerve Growth Factor Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of D-glucose Transmembrane Transport Regulation Of Glycogen Metabolic Process Cell Cortex Regulation Of TRNA Methylation	Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Protein Homodimerization Activity
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