TCL1B and DRC8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCL1B	DRC8
Description		TCL1 family AKT coactivator B	dynein regulatory complex subunit 8
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection Organelle Sperm Principal Piece
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity	Calcium Ion Binding Protein Binding
	Biological Process	Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		17 interacting genes: AKT1 AKT2 APP BAG4 DRC8 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330	5 interacting genes: ANTKMT MRPL12 TCL1B TNNI1 TNNI2
Entrez ID		9623	84288
HPRD ID		04795	14423
Ensembl ID		ENSG00000213231	ENSG00000203666
Uniprot IDs		O95988	Q5VUJ9
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Lsm1-7-Pat1 Complex Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane U4/U6 X U5 Tri-snRNP Complex Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex U6 SnRNP RNA Splicing, Via Transesterification Reactions Negative Regulation Of PERK-mediated Unfolded Protein Response Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Fibroblast Migration U2-type Prespliceosome Nucleus Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Polysaccharide Biosynthetic Process MRNA Catabolic Process Molecular Function Activator Activity U12-type Spliceosomal Complex Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Postsynapse Organization RNA Binding RNA Splicing Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Oxidation Positive Regulation Of Small Molecule Metabolic Process Negative Regulation Of Gene Expression Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Protein Localization To Plasma Membrane Regulation Of Fibroblast Migration Response To Nerve Growth Factor Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of D-glucose Transmembrane Transport Regulation Of Glycogen Metabolic Process Cell Cortex Regulation Of TRNA Methylation	Troponin Complex Skeletal Muscle Contraction Cardiac Muscle Contraction Striated Muscle Contraction Troponin T Binding Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport Muscle Contraction Mitochondrial Transcription Transition Between Fast And Slow Fiber Muscle System Process Peptidyl-lysine Trimethylation Regulation Of Skeletal Muscle Adaptation Actin Binding Peptidyl-lysine Methylation Regulation Of ATP Biosynthetic Process Protein-lysine N-methyltransferase Activity
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