PRDX6 and ORM2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PRDX6	ORM2
Gene Name		peroxiredoxin 6	orosomucoid 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Lysosome Cytosol Membrane Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome	Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Antioxidant Activity Peroxiredoxin Activity
	Biological Process	Response To Reactive Oxygen Species Response To Oxidative Stress Phospholipid Catabolic Process Hydrogen Peroxide Catabolic Process Oxidation-reduction Process	Regulation Of Immune System Process Transport Acute-phase Response
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CASP10 CASP8 GPX4 HNF4G NCF2 NR4A1 ORM2 PAXIP1 PPARD RARA SUMO4 TERF1 TERF2IP UCHL5	3 interactors: CYP39A1 PRDX6 STK3
Entrez ID		9588	5005
HPRD ID		03817	00725
Ensembl ID		ENSG00000117592	ENSG00000228278
Uniprot IDs		P30041	P19652
PDB IDs		1PRX	3APU 3APV 3APW 3APX
Enriched GO Terms of Interacting Partners?		Response To Steroid Hormone Intracellular Receptor Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Steroid Hormone Mediated Signaling Pathway Response To Hormone Hormone-mediated Signaling Pathway Cellular Response To Organic Cyclic Compound Response To Stress Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Regulation Of Apoptotic Process DNA-templated Transcription, Initiation Response To Stimulus Regulation Of Cell Death Cellular Response To Hormone Stimulus Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Epithelial Cell Migration Response To Organic Substance Epithelium Migration Cellular Response To Organic Substance Response To Estradiol Regulation Of Telomere Maintenance Positive Regulation Of Intracellular Signal Transduction RNA-dependent DNA Replication Cellular Response To Lipid Cardiovascular System Development Response To Vitamin A Transcription, DNA-templated Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Ameboidal-type Cell Migration Telomere Maintenance Via Telomere Lengthening Developmental Process RNA Biosynthetic Process Regulation Of Chromosome Organization Response To Estrogen Adipose Tissue Development Positive Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Programmed Cell Death Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cell Death Connective Tissue Development Macromolecule Biosynthetic Process Response To Activity Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Cellular Nitrogen Compound Metabolic Process	Response To Reactive Oxygen Species Lipid Catabolic Process Bile Acid Catabolic Process Response To Oxidative Stress Primitive Hemopoiesis Cholesterol Catabolic Process Regulation Of Axon Regeneration Hydrogen Peroxide Catabolic Process Endocardium Development Hepatocyte Apoptotic Process Bile Acid Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Steroid Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Phospholipid Catabolic Process Hippo Signaling Embryonic Hemopoiesis Hydrogen Peroxide Metabolic Process Cell Differentiation Involved In Embryonic Placenta Development Bile Acid Metabolic Process Negative Regulation Of Organ Growth
Tagcloud ?		1g accompanied activities altered bifunctional carcinogen ccl5 ccr5 clear colocalized cytokine definitive especially glutathione gpx ipla2 jak2 lung mice pathophysiological peroxidase promotes stat3 tg though transgenic tumors urethane validated	9q31 a1l4r1 af495724 ambp belgian boundaries c9orf91 ensestg000000230601 flanking french genotyped intronic kif12 linkage lying orm1 portuguese positional refine replicate resequence resequenced rs3181357 spa spa2 spondylarthritis tnfsf15 tnfsf8 znf618
Tagcloud (Difference) ?		1g accompanied activities altered bifunctional carcinogen ccl5 ccr5 clear colocalized cytokine definitive especially glutathione gpx ipla2 jak2 lung mice pathophysiological peroxidase promotes stat3 tg though transgenic tumors urethane validated	9q31 a1l4r1 af495724 ambp belgian boundaries c9orf91 ensestg000000230601 flanking french genotyped intronic kif12 linkage lying orm1 portuguese positional refine replicate resequence resequenced rs3181357 spa spa2 spondylarthritis tnfsf15 tnfsf8 znf618
Tagcloud (Intersection) ?