ORM2 and PRDX6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ORM2	PRDX6
Gene Name		orosomucoid 2	peroxiredoxin 6
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome Blood Microparticle	Extracellular Space Cytoplasm Lysosome Cytosol Membrane Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome
	Molecular Function		Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Antioxidant Activity Peroxiredoxin Activity
	Biological Process	Regulation Of Immune System Process Transport Acute-phase Response	Response To Reactive Oxygen Species Response To Oxidative Stress Phospholipid Catabolic Process Hydrogen Peroxide Catabolic Process Oxidation-reduction Process
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CYP39A1 PRDX6 STK3	14 interactors: CASP10 CASP8 GPX4 HNF4G NCF2 NR4A1 ORM2 PAXIP1 PPARD RARA SUMO4 TERF1 TERF2IP UCHL5
Entrez ID		5005	9588
HPRD ID		00725	03817
Ensembl ID		ENSG00000228278	ENSG00000117592
Uniprot IDs		P19652	P30041
PDB IDs		3APU 3APV 3APW 3APX	1PRX
Enriched GO Terms of Interacting Partners?		Response To Reactive Oxygen Species Lipid Catabolic Process Bile Acid Catabolic Process Response To Oxidative Stress Primitive Hemopoiesis Cholesterol Catabolic Process Regulation Of Axon Regeneration Hydrogen Peroxide Catabolic Process Endocardium Development Hepatocyte Apoptotic Process Bile Acid Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Steroid Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Phospholipid Catabolic Process Hippo Signaling Embryonic Hemopoiesis Hydrogen Peroxide Metabolic Process Cell Differentiation Involved In Embryonic Placenta Development Bile Acid Metabolic Process Negative Regulation Of Organ Growth	Response To Steroid Hormone Intracellular Receptor Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Steroid Hormone Mediated Signaling Pathway Response To Hormone Hormone-mediated Signaling Pathway Cellular Response To Organic Cyclic Compound Response To Stress Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Regulation Of Apoptotic Process DNA-templated Transcription, Initiation Response To Stimulus Regulation Of Cell Death Cellular Response To Hormone Stimulus Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Epithelial Cell Migration Response To Organic Substance Epithelium Migration Cellular Response To Organic Substance Response To Estradiol Regulation Of Telomere Maintenance Positive Regulation Of Intracellular Signal Transduction RNA-dependent DNA Replication Cellular Response To Lipid Cardiovascular System Development Response To Vitamin A Transcription, DNA-templated Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Ameboidal-type Cell Migration Telomere Maintenance Via Telomere Lengthening Developmental Process RNA Biosynthetic Process Regulation Of Chromosome Organization Response To Estrogen Adipose Tissue Development Positive Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Programmed Cell Death Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cell Death Connective Tissue Development Macromolecule Biosynthetic Process Response To Activity Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		9q31 a1l4r1 af495724 ambp belgian boundaries c9orf91 ensestg000000230601 flanking french genotyped intronic kif12 linkage lying orm1 portuguese positional refine replicate resequence resequenced rs3181357 spa spa2 spondylarthritis tnfsf15 tnfsf8 znf618	1g accompanied activities altered bifunctional carcinogen ccl5 ccr5 clear colocalized cytokine definitive especially glutathione gpx ipla2 jak2 lung mice pathophysiological peroxidase promotes stat3 tg though transgenic tumors urethane validated
Tagcloud (Difference) ?		9q31 a1l4r1 af495724 ambp belgian boundaries c9orf91 ensestg000000230601 flanking french genotyped intronic kif12 linkage lying orm1 portuguese positional refine replicate resequence resequenced rs3181357 spa spa2 spondylarthritis tnfsf15 tnfsf8 znf618	1g accompanied activities altered bifunctional carcinogen ccl5 ccr5 clear colocalized cytokine definitive especially glutathione gpx ipla2 jak2 lung mice pathophysiological peroxidase promotes stat3 tg though transgenic tumors urethane validated
Tagcloud (Intersection) ?