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PRDX6
Gene Name
peroxiredoxin 6
Image
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Lysosome
Cytosol
Membrane
Cytoplasmic Membrane-bounded Vesicle
Extracellular Vesicular Exosome
Molecular Function
Glutathione Peroxidase Activity
Phospholipase A2 Activity
Protein Binding
Antioxidant Activity
Peroxiredoxin Activity
Biological Process
Response To Reactive Oxygen Species
Response To Oxidative Stress
Phospholipid Catabolic Process
Hydrogen Peroxide Catabolic Process
Oxidation-reduction Process
Pathways
Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-protein Interactions
14 interactors:
CASP10
CASP8
GPX4
HNF4G
NCF2
NR4A1
ORM2
PAXIP1
PPARD
RARA
SUMO4
TERF1
TERF2IP
UCHL5
Entrez ID
9588
HPRD ID
03817
Ensembl ID
ENSG00000117592
Uniprot IDs
P30041
PDB IDs
1PRX
Enriched GO Terms of Interacting Partners
?
Response To Steroid Hormone
Intracellular Receptor Signaling Pathway
Response To Lipid
Response To Organic Cyclic Compound
Steroid Hormone Mediated Signaling Pathway
Response To Hormone
Hormone-mediated Signaling Pathway
Cellular Response To Organic Cyclic Compound
Response To Stress
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Regulation Of Apoptotic Process
DNA-templated Transcription, Initiation
Response To Stimulus
Regulation Of Cell Death
Cellular Response To Hormone Stimulus
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Epithelial Cell Migration
Response To Organic Substance
Epithelium Migration
Cellular Response To Organic Substance
Response To Estradiol
Regulation Of Telomere Maintenance
Positive Regulation Of Intracellular Signal Transduction
RNA-dependent DNA Replication
Cellular Response To Lipid
Cardiovascular System Development
Response To Vitamin A
Transcription, DNA-templated
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Ameboidal-type Cell Migration
Telomere Maintenance Via Telomere Lengthening
Developmental Process
RNA Biosynthetic Process
Regulation Of Chromosome Organization
Response To Estrogen
Adipose Tissue Development
Positive Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Programmed Cell Death
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cell Death
Connective Tissue Development
Macromolecule Biosynthetic Process
Response To Activity
Regulation Of Proteolysis
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Signal Transduction
Cellular Nitrogen Compound Metabolic Process
Tagcloud
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1g
accompanied
activities
altered
bifunctional
carcinogen
ccl5
ccr5
clear
colocalized
cytokine
definitive
especially
glutathione
gpx
ipla2
jak2
lung
mice
pathophysiological
peroxidase
promotes
stat3
tg
though
transgenic
tumors
urethane
validated