BRE and BABAM1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		BRE	BABAM1
Gene Name		brain and reproductive organ-expressed (TNFRSF1A modulator)	BRISC and BRCA1 A complex member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Ubiquitin Ligase Complex Nucleus Cytoplasm BRCA1-A Complex BRISC Complex	Nucleus Nucleoplasm Cytoplasm BRCA1-A Complex BRISC Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Tumor Necrosis Factor Receptor Binding Protein Binding Polyubiquitin Binding	Protein Binding
	Biological Process	Double-strand Break Repair Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Response To Ionizing Radiation Chromatin Modification G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair	Double-strand Break Repair Response To Ionizing Radiation Chromatin Modification G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Protein K63-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		7 interactors: BABAM1 FAM175A GFI1B NCOA3 SUMO2 UBC UBE2D1	5 interactors: BRCA1 BRE TERF2IP TRIM27 UIMC1
Entrez ID		9577	29086
HPRD ID		08498	13702
Ensembl ID		ENSG00000158019	ENSG00000105393
Uniprot IDs		Q9NXR7	M0QX07 Q9NWV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Checkpoint Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process DNA Damage Checkpoint Positive Regulation Of Cellular Metabolic Process Chromatin Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Catabolic Process Chromatin Organization Positive Regulation Of DNA Repair G2 DNA Damage Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Chromosome Organization Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA Repair Regulation Of DNA-templated Transcription In Response To Stress Cell Cycle Process Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Response To Abiotic Stimulus TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Nucleobase-containing Compound Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell Cycle Regulation Of Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Protein Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stress DNA Repair Cellular Nitrogen Compound Metabolic Process Regulation Of Response To DNA Damage Stimulus	Regulation Of DNA Repair Regulation Of Response To DNA Damage Stimulus G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Double-strand Break Repair DNA Damage Checkpoint Cellular Response To DNA Damage Stimulus Cell Cycle Checkpoint DNA Metabolic Process Organelle Organization Response To Radiation Response To Stress Cellular Response To Stress Negative Regulation Of Chromosome Organization DNA Repair Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of DNA Recombination At Telomere Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Organelle Organization Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Histone H2A K63-linked Deubiquitination Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Regulation Of Gene Expression, Epigenetic Chromosome Organization Cell Cycle Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Protection From Non-homologous End Joining At Telomere Cellular Response To Indole-3-methanol Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Telomere Capping Protein Localization To Chromosome, Telomeric Region
Tagcloud ?		cdna cerebellar damaging encodes fas gives homologous hybrid immunoprecipitation interacted irradiation juxtamembrane kb kilodaltons library modulate neurotrophin nfkappab organs p55 p75 reproductive responsive rise screen tnf uv verified yeast
Tagcloud (Difference) ?		cdna cerebellar damaging encodes fas gives homologous hybrid immunoprecipitation interacted irradiation juxtamembrane kb kilodaltons library modulate neurotrophin nfkappab organs p55 p75 reproductive responsive rise screen tnf uv verified yeast
Tagcloud (Intersection) ?