BABAM2

Name	BRISC and BRCA1 A complex member 2
Structure
Novel Interactors	1 novel interactors: VRK2
Interactors	7 interactors: BABAM1 GFI1B NCOA3 PPDPF SUMO2 UBC UBE2D1
GO Annotations	Cellular Component	Nuclear Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Tumor Necrosis Factor Receptor Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	DNA Repair Regulation Of DNA Repair Double-strand Break Repair Chromatin Organization Apoptotic Process DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Signal Transduction Response To Ionizing Radiation Negative Regulation Of Apoptotic Process Mitotic G2/M Transition Checkpoint Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination Cellular Response To Ionizing Radiation Regulation Of DNA Damage Checkpoint
Pathways	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
GWAS	Blond vs. brown/black hair color ( 30531825 ) Estimated glomerular filtration rate ( 31152163 ) Intraocular pressure ( 29617998 ) Low density lipoprotein cholesterol levels ( 33339817 ) Urate levels ( 31578528 ) Uterine fibroids ( 31649266 )
Entrez ID	9577
HPRD ID	08498
Ensembl ID	ENSG00000158019
Uniprot IDs	Q9NXR7
PDB IDs	6H3C 6R8F 8PVY 8PY2
GO Terms Enriched among Interactors ?	Protein Tag Activity TORC1 Signaling Organelle Envelope