ABHD16A and RETREG3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABHD16A	RETREG3
Description		abhydrolase domain containing 16A, phospholipase	reticulophagy regulator family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex Endoplasmic Reticulum Tubular Network
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity	Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity
	Biological Process	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process	Autophagy Endoplasmic Reticulum Organization Positive Regulation Of Neuron Projection Development Collagen Catabolic Process Reticulophagy Substrate Localization To Autophagosome Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L	107 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARL6IP1 ARLN ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 JAGN1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6
Entrez ID		7920	162427
HPRD ID		15929	14108
Ensembl ID		ENSG00000204427	ENSG00000141699
Uniprot IDs		A0A1U9X777 B3KNX9 O95870	K7EQI9 Q86VR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endomembrane System Organelle Fusion Organelle Membrane Fusion Membrane Organization Golgi Vesicle Transport Vesicle Fusion Protein Binding Organelle Localization By Membrane Tethering Vesicle Organization Lipid Biosynthetic Process Membrane Docking SNARE Binding Golgi Membrane Vesicle-mediated Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Response To Nitrogen Starvation Endoplasmic Reticulum Organization Vesicle Docking CDP-diacylglycerol Metabolic Process Transport Vesicle SNARE Complex Assembly Mitochondrial Outer Membrane Phosphatidylethanolamine Binding FFAT Motif Binding Endoplasmic Reticulum Membrane Organization Organelle Membrane Bounding Membrane Of Organelle Synaptic Vesicle Phospholipid Metabolic Process Azurophil Granule Membrane COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Phospholipid Biosynthetic Process Lipid Metabolic Process Establishment Of Protein Localization Late Endosome Menaquinone Metabolic Process Negative Regulation Of Sphingolipid Biosynthetic Process Chloride Channel Inhibitor Activity Endoplasmic Reticulum Localization Serine Palmitoyltransferase Complex Positive Regulation Of B Cell Receptor Signaling Pathway
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