ABHD16A and AQP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABHD16A	AQP7
Description		abhydrolase domain containing 16A, phospholipase	aquaporin 7
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Lipid Droplet Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity
	Biological Process	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process	Water Transport Glycerol Transmembrane Transport Transmembrane Transport Urea Transmembrane Transport
Pathways			Transport of glycerol from adipocytes to the liver by Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)	Lung adenocarcinoma ( 28604730) Urinary albumin excretion ( 30220432)
Interacting Genes		69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L	4 interacting genes: ABHD16A CLCN7 COMT MFSD6
Entrez ID		7920	364
HPRD ID		15929	04277
Ensembl ID		ENSG00000204427	ENSG00000165269
Uniprot IDs		A0A1U9X777 B3KNX9 O95870	B7Z4U2 O14520 Q5T5M0 Q6P5T0
PDB IDs			6KXW 6N1G 6QZI 6QZJ 8AMW 8AMX 8C9H
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum	Chloride:proton Antiporter Activity Cellular Response To Phosphate Starvation Norepinephrine Secretion Catechol O-methyltransferase Activity Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Transepithelial Chloride Transport O-methyltransferase Activity Renal Tubular Secretion Dopamine Secretion Habituation Renal Protein Absorption Mastication Catecholamine Catabolic Process Renal Sodium Excretion Renal Albumin Absorption Norepinephrine Transport Nonassociative Learning Renin Secretion Into Blood Stream Cellular Response To Cocaine Response To Dopamine Dopamine Catabolic Process Catecholamine Secretion Cerebellar Cortex Morphogenesis Monoacylglycerol Catabolic Process Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Monoacylglycerol Lipase Activity Synaptic Transmission, Dopaminergic Glomerulus Development Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Norepinephrine Metabolic Process Startle Response Response To Corticosterone Phosphatidylserine Metabolic Process Chloride Transmembrane Transporter Activity Renal Filtration Dopamine Transport Response To Catecholamine Detection Of Temperature Stimulus Involved In Sensory Perception Phosphatidylcholine Lysophospholipase Activity Detection Of Temperature Stimulus Response To Salt Glycerophospholipid Catabolic Process Response To Angiotensin Phospholipase Activity Acylglycerol Catabolic Process Cholesterol Efflux Monoamine Transport Dopamine Metabolic Process
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