ABHD16A and MT-ND4

Number of citations of the paper that reports this interaction (PubMedID 14667819)
0

Data Source:
HPRD (two hybrid)

		ABHD16A	MT-ND4
Description		abhydrolase domain containing 16A, phospholipase	NADH dehydrogenase subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity	NADH Dehydrogenase Activity NADH Dehydrogenase (ubiquinone) Activity Ubiquinone Binding
	Biological Process	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process	Response To Hypoxia In Utero Embryonic Development Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Cerebellum Development Mitochondrial Respiratory Chain Complex I Assembly Response To Nicotine ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Response To Ethanol
Pathways			Mitochondrial translation termination Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases			Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L	7 interacting genes: ABHD16A APC ATM CTCF GRB2 LIG4 NKX3-1
Entrez ID		7920	4538
HPRD ID		15929	08954
Ensembl ID		ENSG00000204427	ENSG00000198886
Uniprot IDs		A0A1U9X777 B3KNX9 O95870	H9EC08 P03905
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum	DNA Damage Response Regulation Of Chromosome Organization Cellular Response To Ionizing Radiation Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Organelle Organization Response To X-ray Cellular Response To Radiation Response To Ionizing Radiation V(D)J Recombination Condensed Chromosome Negative Regulation Of Cell Population Proliferation Cellular Response To Stress Negative Regulation Of Mitotic Nuclear Division Cellular Developmental Process Regulation Of Cell Population Proliferation Somitogenesis Somatic Cell DNA Recombination Heart Development Segmentation Response To Gamma Radiation Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Mitotic Sister Chromatid Separation Pattern Specification Process Negative Regulation Of Chromosome Organization Insulin Receptor Signaling Pathway Tissue Morphogenesis Regulation Of Cell Cycle Regulation Of Chromosome Separation Guanyl-nucleotide Exchange Factor Adaptor Activity Establishment Of Integrated Proviral Latency Positive Regulation Of Androgen Secretion MADS Box Domain Binding Chromatin Loop Anchoring Activity Positive Regulation Of Cellular Component Organization Response To Radiation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Sister Chromatid Segregation Regulation Of Mitotic Cell Cycle Nucleoplasm Protein Localization To Chromosome Establishment Of RNA Localization To Telomere Establishment Of Protein-containing Complex Localization To Telomere Positive Regulation Of Organelle Organization Positive Regulation Of Chromosome Organization Positive Regulation Of Telomerase Catalytic Core Complex Assembly Grb2-EGFR Complex Establishment Of Viral Latency Dorsal Aorta Development Phosphatidylserine Catabolic Process
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