ABHD16A and BRI3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABHD16A	BRI3
Description		abhydrolase domain containing 16A, phospholipase	brain protein I3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Cytoplasm Lysosome Lysosomal Membrane Plasma Membrane Membrane Azurophil Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity	Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)	Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L	3 interacting genes: ABHD16A BACE1 MALL
Entrez ID		7920	25798
HPRD ID		15929	16562
Ensembl ID		ENSG00000204427	ENSG00000164713
Uniprot IDs		A0A1U9X777 B3KNX9 O95870	O95415
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum	Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Golgi-associated Vesicle Lumen Beta-aspartyl-peptidase Activity Membrane Raft Monoacylglycerol Catabolic Process Structural Constituent Of Myelin Sheath Monoacylglycerol Lipase Activity Phospholipase Activity Phosphatidylserine Metabolic Process Acylglycerol Catabolic Process Glycerophospholipid Catabolic Process Phosphatidylcholine Lysophospholipase Activity Prepulse Inhibition Membrane Protein Ectodomain Proteolysis Amyloid-beta Formation Aspartic-type Endopeptidase Activity Response To Manganese Ion Amyloid Precursor Protein Metabolic Process Amyloid Precursor Protein Catabolic Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Cellular Response To Copper Ion Amyloid-beta Metabolic Process Response To Lead Ion Cellular Response To Manganese Ion Protein Serine/threonine Kinase Binding Detection Of Mechanical Stimulus Involved In Sensory Perception Amyloid Fibril Formation Modified Amino Acid Catabolic Process Response To Copper Ion Membrane Protein Proteolysis Cytoplasmic Vesicle Phospholipid Catabolic Process Presynaptic Modulation Of Chemical Synaptic Transmission Detection Of Mechanical Stimulus Hippocampal Mossy Fiber To CA3 Synapse Multivesicular Body Signaling Receptor Ligand Precursor Processing Cellular Response To Amyloid-beta Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Clathrin-coated Vesicle Fatty Acid Derivative Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Endopeptidase Activity Amyloid-beta Binding Sterol Homeostasis Cholesterol Homeostasis Myelination
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