CXCL14 and CXCL10

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL14	CXCL10
Description		C-X-C motif chemokine ligand 14	C-X-C motif chemokine ligand 10
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity	Signaling Receptor Binding Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CAMP-dependent Protein Kinase Regulator Activity Chemoattractant Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Signal Transduction Cell-cell Signaling Killing Of Cells Of Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Muscle Organ Development Blood Circulation Positive Regulation Of Cell Population Proliferation Response To Bacterium Response To Gamma Radiation T Cell Chemotaxis Regulation Of T Cell Chemotaxis Response To Auditory Stimulus Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Killing Of Cells Of Another Organism Response To Lipopolysaccharide Response To Vitamin D Cellular Response To Heat Endothelial Cell Activation Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Chemotaxis Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Monocyte Chemotaxis Cellular Response To Interleukin-17 Cellular Response To Virus Antiviral Innate Immune Response Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Myoblast Fusion Positive Regulation Of T Cell Migration
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs			N-Methylleucine Eldelumab Clove oil
Diseases
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321)	Blood protein levels ( 30072576) C-X-C motif chemokine 10 levels ( 25147954) Hippocampal volume ( 29274321) Interferon gamma-induced protein 10 levels ( 27989323 31217265) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		28 interacting genes: APP CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CXCL10 CXCL11 CXCL12 CXCL17 CXCL2 CXCL5 CXCL9 F2R GPR85 JMJD6 KLRC1 LMNA PF4 PPBP REL ROBO3 SLAMF6 TEX11 TNFRSF10C TRIM23 XCL1	22 interacting genes: CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CCR3 CXCL11 CXCL12 CXCL14 CXCL17 CXCL6 CXCL9 CXCR3 DPP4 IGFBP7 PF4 PF4V1 PPBP VCAN XCL1
Entrez ID		9547	3627
HPRD ID		16049	00930
Ensembl ID		ENSG00000145824	ENSG00000169245
Uniprot IDs		O95715	P02778
PDB IDs		2HDL	1LV9 1O7Y 1O7Z 1O80 8K2X
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemotaxis Leukocyte Chemotaxis Locomotion Cell Chemotaxis Humoral Immune Response Cytokine Activity Granulocyte Chemotaxis Defense Response To Symbiont Defense Response To Other Organism Leukocyte Migration Myeloid Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Response To External Biotic Stimulus Response To Other Organism Immune System Process Defense Response Immune Response Inflammatory Response CXCR Chemokine Receptor Binding Chemokine-mediated Signaling Pathway Cell Killing Cell Migration Cell Motility Mononuclear Cell Migration Chemokine Receptor Binding Neutrophil Chemotaxis CCR Chemokine Receptor Binding G Protein-coupled Receptor Signaling Pathway Extracellular Space Response To Stress Neutrophil Migration Positive Regulation Of T Cell Migration Cytokine-mediated Signaling Pathway CXCR3 Chemokine Receptor Binding Regulation Of Chemotaxis Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Eosinophil Chemotaxis Extracellular Region Positive Regulation Of Leukocyte Chemotaxis Regulation Of T Cell Migration Positive Regulation Of Mononuclear Cell Migration Eosinophil Migration Positive Regulation Of Calcium Ion Transport Regulation Of Locomotion Positive Regulation Of Monocyte Chemotaxis	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Leukocyte Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Leukocyte Migration Cytokine Activity Cell Migration Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Myeloid Leukocyte Migration Humoral Immune Response Granulocyte Migration Cell Motility Killing Of Cells Of Another Organism Inflammatory Response Defense Response Cell Killing CXCR Chemokine Receptor Binding Cytokine-mediated Signaling Pathway Extracellular Space Immune Response Defense Response To Symbiont Immune System Process Defense Response To Other Organism Extracellular Region CCR Chemokine Receptor Binding Response To Other Organism Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Response To External Biotic Stimulus Eosinophil Chemotaxis Eosinophil Migration Neutrophil Chemotaxis Chemokine Receptor Binding Neutrophil Migration Regulation Of Leukocyte Migration Response To Stress Lymphocyte Chemotaxis Regulation Of Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Locomotion Cell-cell Signaling Signaling Signal Transduction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?