BAG4 and ATAD2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		BAG4	ATAD2
Description		BAG cochaperone 4	ATPase family AAA domain containing 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Protein-folding Chaperone Binding	Nucleotide Binding Chromatin Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding
	Biological Process	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Protein Stabilization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of MRNA Modification Ruffle Assembly Negative Regulation Of Protein Targeting To Mitochondrion	Nucleosome Assembly Nucleosome Disassembly Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription
Pathways		Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		141 interacting genes: ABI2 ACOT7 ADAMTSL4 ALG13 ANKHD1 APOBEC1 ARID5A ATAD2 ATOSB ATP23 BAP1 BCAS3 BCL2 BCL6B BEX1 BLZF1 BMS1 C3orf38 CASP2 CASZ1 CBFA2T2 CCL5 CEP55 CIMAP1C CPSF7 DDIT4L DIRAS3 DMRTB1 DZIP3 EFEMP1 EIF4ENIF1 EPSTI1 ERRFI1 FAM222B FARS2 FTH1 FYN GLCE GPANK1 GPS2 GRAP2 GRIP1 HOXA1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8 IL13RA2 IL24 IST1 ITIH5 KCTD6 KCTD7 KIF5B KLK5 KLK7 KLK9 KRT31 KRTAP13-1 KRTAP13-4 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP6-3 LASP1 LRATD2 LYPD3 MAGED1 MEI4 MRC2 MTA3 MYOZ1 MYOZ3 MYPOP NAT2 ODF1 P4HA3 PDCD6 PDLIM2 PEF1 PGRMC2 PHF19 PKP2 PLAC8 PPIL6 PRDM14 PRPF6 PRRC2B PSMB5 PYCR3 QKI RAMAC RASL10B RBFOX2 RBM22 RBM42 RBM7 RBPMS RHOBTB2 RNF20 RPL22 RUNX1 SAMD4A SAXO1 SAXO4 SCGB3A1 SF1 SF3B4 SH3RF2 SIAH1 SNRPA SNRPB SNRPC SNRPN SNW1 SS18L1 SUOX TBC1D3B TBC1D3G TBC1D7 TCL1B TEKT5 TFAP2D TFIP11 THRSP TINAGL1 TLE5 TNFRSF1A TNFRSF25 TRAPPC6A TSG101 UNKL USP22 VIM VPS37C ZBTB45 ZBTB5 ZIM2	12 interacting genes: BAG4 BCAR3 CASP8 E2F1 E2F2 E2F3 E2F4 ESR1 H3-4 H4C14 MYC NCOA3
Entrez ID		9530	29028
HPRD ID		04861	10678
Ensembl ID		ENSG00000156735	ENSG00000156802
Uniprot IDs		O95429	Q6PL18
PDB IDs		1M62 1M7K	3DAI 4QSP 4QSQ 4QSR 4QSS 4QST 4QSU 4QSV 4QSW 4QSX 4QUT 4QUU 4TT2 4TT4 4TT6 4TTE 4TU4 4TU6 4TYL 4TZ2 4TZ8 5A5N 5A5O 5A5P 5A5Q 5A5R 5A81 5A82 5A83 5EPB 5F36 5F3A 5LJ0 5QXI 5QXJ 5QXK 5QXL 5QXM 5QXN 5QXO 5QXP 5QXQ 5QXR 5QXS 5QXT 5QXU 5QXV 5QXW 5QXX 5QXY 5QXZ 5QY0 5R4E 5R4F 5R4V 5R4W 5R4X 5R4Y 5R4Z 6CPS 6EPJ 6EPR 6EPS 6EPT 6EPU 6EPV 6EPW 6EPX 6HDN 6HDO 6HI3 6HI4 6HI5 6HI6 6HI7 6HI8 6HIA 6HIB 6HIC 6HID 6HIE 6S55 6S56 6S57 6YB4 7M98 7PPX 7PX5 7Q6T 7Q6U 7Q6V 7Q6W 7QU7 7QUK 7QUM 7QWO 7QX1 7QXT 7QYK 7QYL 7QZM 7QZY 7QZZ 7R00 7R05 7R0Y 7Z9H 7Z9I 7Z9J 7Z9N 7Z9O 7Z9S 7Z9U 8H3H 8JUW 8JUY 8JUZ 8RU5 8SDO 8SDQ
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Protein Refolding MRNA Metabolic Process MRNA Processing ATP-dependent Protein Folding Chaperone Intermediate Filament RNA Binding RNA Splicing Protein Binding Hair Cycle C3HC4-type RING Finger Domain Binding Transcription Corepressor Activity ATP-dependent Protein Disaggregase Activity Protein Folding Chaperone Cellular Heat Acclimation Nucleus Heat Shock Protein Binding U1 SnRNP U4/U6 X U5 Tri-snRNP Complex Regulation Of RNA Splicing RNA Processing RNA Metabolic Process Negative Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Catalytic Step 2 Spliceosome Regulation Of MRNA Metabolic Process Identical Protein Binding Negative Regulation Of Post-translational Protein Modification Negative Regulation Of Inclusion Body Assembly Keratin Filament Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Post-translational Protein Modification SnRNP Binding Negative Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Binding MRNA Binding Response To Temperature Stimulus Nucleic Acid Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome U2-type Prespliceosome Unfolded Protein Binding Positive Regulation Of Antibacterial Peptide Production Epidermal Lamellar Body Macromolecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Calcium-dependent Protein Binding Blood Microparticle	Protein Dimerization Activity Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex DNA-binding Transcription Activator Activity RNA Polymerase II Transcription Regulator Complex Chromatin DNA-binding Transcription Factor Activity Lens Fiber Cell Apoptotic Process Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Protein-containing Complex Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Regulation Of Fibroblast Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Developmental Process Chromatin Remodeling Apoptotic Signaling Pathway Response To Estradiol Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Regulation Of Apoptotic Process Regulation Of Multicellular Organismal Development Nucleoplasm Nucleobase-containing Compound Biosynthetic Process Sequence-specific DNA Binding Intrinsic Apoptotic Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of Cell Population Proliferation Protein-DNA Complex Assembly Cellular Response To Estradiol Stimulus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Smooth Muscle Cell Apoptotic Process Regulation Of Cell Differentiation Positive Regulation Of Apoptotic Process Transcription Coregulator Binding Regulation Of Myeloid Cell Differentiation Positive Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Epithelial Cell Apoptotic Process
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